C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: G protein-coupled receptor kinase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000031450 Grk1 10090 + 8:13405081-13421945 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000033827 Grk1-201 13405081-13421945 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000033827
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000033827 0.156±0.04 0.173±0.04 0.291±0.05 0.521±0.44 0.140±0.08 0.128±0.04 0.100±0.02 0.104±0.03 0.140±0.05 0.113±0.01 0.094±0.02 0.222±0.12 0.189±0.12 0.220±0.10

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000SN CIL_0000SN_0002 CGP 8:13386209-13421945
CIL_0000SF CIL_0000SF_0002 CGP 8:13405081-13461452

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004703 IEA G-protein coupled receptor kinase activity
GO:0005524 IEA ATP binding
GO:0007165 IEA signal transduction
GO:0008594 IMP photoreceptor cell morphogenesis
GO:0009416 IMP response to light stimulus
GO:0022400 IEA regulation of rhodopsin mediated signaling pathway
GO:0038032 IEA termination of G-protein coupled receptor signaling pathway
GO:0042327 IMP positive regulation of phosphorylation
GO:0043066 IMP negative regulation of apoptotic process
GO:0046777 IEA protein autophosphorylation
GO:0050254 IEA rhodopsin kinase activity
GO:0060060 IMP post-embryonic retina morphogenesis in camera-type eye

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000058803 grk1a G protein-coupled receptor kinase 1 a protein_coding Danio_rerio
ENSG00000185974 GRK1 G protein-coupled receptor kinase 1 protein_coding Homo_sapiens

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