C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: polo-like kinase 5
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000185988 PLK5 9606 + 19:1524074-1535456 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000334770 PLK5-002 1524959-1535456 protein_coding
  ENST00000454744 PLK5-001 1524074-1535453 protein_coding
  ENST00000588292 PLK5-004 1528337-1529048 retained_intron
  ENST00000588430 PLK5-003 1526997-1535250 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBrainBreastColonHeartLungOvaryPlacentaTestisENST00000334770ENST00000454744ENST00000588292ENST00000588430
Transcript ID Adrenal Brain Breast Colon Heart Lung Ovary Placenta Testis
ENST00000334770 N/A N/A N/A N/A N/A N/A 0.105±0.00 0.043±0.00 0.552±0.00
ENST00000454744 0.092±0.00 0.269±0.11 0.064±0.00 N/A 0.018±0.00 N/A 0.183±0.11 0.162±0.06 2.195±2.01
ENST00000588292 N/A N/A N/A N/A N/A N/A 0.278±0.00 N/A N/A
ENST00000588430 N/A 0.914±0.00 N/A 0.397±0.00 N/A 0.044±0.00 0.030±0.00 N/A 1.567±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000ZK CIL_0000ZK_0001 CGP 19:1505018-1535456
CIL_00066Y CIL_00066Y_0001 CGP 19:1524074-1568058

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002357 IDA defense response to tumor cell
GO:0004672 IEA protein kinase activity
GO:0005524 IEA ATP binding
GO:0005634 IEA nucleus
GO:0005737 IDA cytoplasm
GO:0006468 IEA protein phosphorylation
GO:0006927 IMP transformed cell apoptotic process
GO:0007067 IEA mitotic nuclear division
GO:0010976 IDA positive regulation of neuron projection development
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0031572 IMP G2 DNA damage checkpoint
GO:0071363 IDA cellular response to growth factor stimulus
GO:2000045 IMP regulation of G1/S transition of mitotic cell cycle

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000035486 Plk5 polo-like kinase 5 protein_coding Mus_musculus

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