C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: polo-like kinase 5
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000035486 Plk5 10090 + 10:80356459-80365489 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000039836 Plk5-001 80356459-80365489 protein_coding
  ENSMUST00000105351 Plk5-002 80356459-80365489 protein_coding
  ENSMUST00000146826 Plk5-004 80359270-80360785 retained_intron
  ENSMUST00000152544 Plk5-003 80357977-80360527 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000039836ENSMUST00000105351ENSMUST00000146826ENSMUST00000152544
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000039836 N/A N/A N/A N/A 0.287±0.11 0.029±0.00 N/A N/A 1.139±0.00 0.264±0.06 0.305±0.26 0.307±0.10 0.040±0.04 0.136±0.11
ENSMUST00000105351 0.034±0.01 0.149±0.05 1.055±0.07 4.625±4.28 0.193±0.11 0.061±0.01 0.224±0.14 0.270±0.13 0.210±0.17 0.679±0.27 0.351±0.09 1.176±0.62 0.125±0.12 0.278±0.13
ENSMUST00000146826 N/A 0.420±0.00 N/A N/A 0.430±0.18 0.109±0.04 N/A N/A N/A N/A 0.124±0.00 N/A 0.098±0.03 N/A
ENSMUST00000152544 0.037±0.01 0.183±0.00 0.889±0.00 N/A 0.217±0.07 0.098±0.05 N/A 0.261±0.10 0.280±0.38 N/A 0.248±0.00 0.661±0.47 0.100±0.00 0.169±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000ZK CIL_0000ZK_0002 CGP 10:80339110-80365489
CIL_00066Y CIL_00066Y_0002 CGP 10:80356459-80387659

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002357 IEA defense response to tumor cell
GO:0004674 IEA protein serine/threonine kinase activity
GO:0005524 IEA ATP binding
GO:0005730 IDA nucleolus
GO:0005737 IEA cytoplasm
GO:0006468 IEA protein phosphorylation
GO:0006927 IEA transformed cell apoptotic process
GO:0006974 IDA cellular response to DNA damage stimulus
GO:0007049 IEA cell cycle
GO:0008285 IMP negative regulation of cell proliferation
GO:0010976 IEA positive regulation of neuron projection development
GO:0031572 IEA G2 DNA damage checkpoint
GO:0046872 IEA metal ion binding
GO:0051301 IEA cell division
GO:0071363 IEA cellular response to growth factor stimulus
GO:2000045 IEA regulation of G1/S transition of mitotic cell cycle

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000185988 PLK5 polo-like kinase 5 protein_coding Homo_sapiens

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