C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: cytochrome P450, family 4, subfamily F, polypeptide 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000186115 CYP4F2 9606 - 19:15878023-15898120 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000011989 CYP4F2-201 15878300-15898057 protein_coding
  ENST00000221700 CYP4F2-001 15878023-15898120 protein_coding
  ENST00000392846 CYP4F2-002 15878023-15898074 retained_intron
  ENST00000586927 CYP4F2-005 15892373-15897729 protein_coding
  ENST00000587671 CYP4F2-004 15879894-15898071 nonsense_mediated_decay
  ENST00000589654 CYP4F2-007 15878623-15886025 protein_coding
  ENST00000592710 CYP4F2-006 15879637-15886501 retained_intron
  ENST00000608168 CYP4F2-003 15892386-15898077 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryTestisENST00000011989ENST00000221700ENST00000392846ENST00000589654ENST00000592710
Transcript ID Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Testis
ENST00000011989 N/A N/A N/A N/A N/A 0.027±0.00 N/A N/A N/A N/A 0.072±0.05 0.081±0.00
ENST00000221700 N/A 2.286±0.00 0.085±0.00 N/A 0.565±0.00 N/A 23.324±21.11 22.015±0.00 N/A N/A N/A 0.259±0.00
ENST00000392846 0.012±0.00 N/A N/A 0.140±0.00 N/A N/A N/A N/A 0.050±0.00 0.023±0.00 N/A N/A
ENST00000589654 0.037±0.00 N/A N/A 0.053±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000592710 0.045±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.152±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000038 IDA very long-chain fatty acid metabolic process
GO:0001676 IDA long-chain fatty acid metabolic process
GO:0003091 IEP renal water homeostasis
GO:0003095 IEP pressure natriuresis
GO:0005506 IEA iron ion binding
GO:0005515 IPI protein binding
GO:0005737 IDA cytoplasm
GO:0005789 TAS endoplasmic reticulum membrane
GO:0006690 TAS icosanoid metabolic process
GO:0006691 TAS leukotriene metabolic process
GO:0006805 TAS xenobiotic metabolic process
GO:0007596 TAS blood coagulation
GO:0008217 IMP regulation of blood pressure
GO:0008392 IDA arachidonic acid epoxygenase activity
GO:0016324 IDA apical plasma membrane
GO:0016705 IEA oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
GO:0016709 IDA oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
GO:0017144 IMP drug metabolic process
GO:0018685 IDA alkane 1-monooxygenase activity
GO:0019369 IDA arachidonic acid metabolic process
GO:0019373 IDA epoxygenase P450 pathway
GO:0020037 IEA heme binding
GO:0030195 IMP negative regulation of blood coagulation
GO:0032304 IMP negative regulation of icosanoid secretion
GO:0032305 IMP positive regulation of icosanoid secretion
GO:0036101 IDA leukotriene B4 catabolic process
GO:0042360 IDA vitamin E metabolic process
GO:0042361 IDA menaquinone catabolic process
GO:0042371 IMP vitamin K biosynthetic process
GO:0042376 IDA phylloquinone catabolic process
GO:0042377 IDA vitamin K catabolic process
GO:0043231 IDA intracellular membrane-bounded organelle
GO:0044281 TAS small molecule metabolic process
GO:0047057 IMP vitamin-K-epoxide reductase (warfarin-sensitive) activity
GO:0050051 IDA leukotriene-B4 20-monooxygenase activity
GO:0052869 IDA arachidonic acid omega-hydroxylase activity
GO:0052871 IDA alpha-tocopherol omega-hydroxylase activity
GO:0052872 IDA tocotrienol omega-hydroxylase activity
GO:0055078 IEP sodium ion homeostasis
GO:0055114 IEA oxidation-reduction process
GO:0097267 TAS omega-hydroxylase P450 pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000003484 Cyp4f18 cytochrome P450, family 4, subfamily f, polypeptide 18 protein_coding Mus_musculus

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