C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: potassium inwardly-rectifying channel, subfamily J, member 11
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000187486 KCNJ11 9606 - 11:17385859-17389331 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000339994 KCNJ11-001 17385859-17388659 protein_coding
  ENST00000526747 KCNJ11-005 17386063-17386750 processed_transcript
  ENST00000526912 KCNJ11-003 17387370-17389085 protein_coding
  ENST00000528731 KCNJ11-002 17385859-17389331 protein_coding
  ENST00000528992 KCNJ11-004 17387643-17388872 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000339994ENST00000526912ENST00000528731ENST00000528992
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000339994 2.870±0.00 0.854±0.00 0.238±0.00 2.137±1.64 0.691±0.66 0.582±0.00 1.884±1.79 0.994±0.00 N/A 0.119±0.11 16.091±13.51 0.173±0.04 0.186±0.00 1.077±0.00
ENST00000526912 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.056±0.00 N/A
ENST00000528731 N/A N/A N/A N/A N/A 0.196±0.00 N/A 0.936±0.00 0.093±0.00 N/A N/A 0.253±0.15 0.047±0.00 N/A
ENST00000528992 N/A N/A N/A N/A 0.127±0.00 N/A N/A N/A 0.381±0.00 N/A 2.367±0.00 N/A 0.583±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003ZU CIL_0003ZU_0001 CGP 11:17385859-17476845

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002931 IEA response to ischemia
GO:0005242 IEA inward rectifier potassium channel activity
GO:0005249 IDA voltage-gated potassium channel activity
GO:0005515 IEA protein binding
GO:0005524 ISS ATP binding
GO:0005635 IEA nuclear envelope
GO:0005739 IEA mitochondrion
GO:0005768 IEA endosome
GO:0005783 IEA endoplasmic reticulum
GO:0005829 IEA cytosol
GO:0005886 IDA plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006006 IMP glucose metabolic process
GO:0006112 TAS energy reserve metabolic process
GO:0006813 IEA potassium ion transport
GO:0007268 TAS synaptic transmission
GO:0008022 IEA protein C-terminus binding
GO:0008076 IDA voltage-gated potassium channel complex
GO:0008282 ISS ATP-sensitive potassium channel complex
GO:0010107 ISS potassium ion import
GO:0014704 IEA intercalated disc
GO:0015272 ISS ATP-activated inward rectifier potassium channel activity
GO:0016021 IEA integral component of membrane
GO:0030315 ISS T-tubule
GO:0030506 IPI ankyrin binding
GO:0030673 IEA axolemma
GO:0030955 TAS potassium ion binding
GO:0031072 IEA heat shock protein binding
GO:0032355 IEA response to estradiol
GO:0033198 IDA response to ATP
GO:0033574 IEA response to testosterone
GO:0042383 IEA sarcolemma
GO:0042391 IDA regulation of membrane potential
GO:0042493 IMP response to drug
GO:0043025 IEA neuronal cell body
GO:0043209 IEA myelin sheath
GO:0043231 IEA intracellular membrane-bounded organelle
GO:0044281 TAS small molecule metabolic process
GO:0044325 IPI ion channel binding
GO:0046676 IMP negative regulation of insulin secretion
GO:0050796 IMP regulation of insulin secretion
GO:0050877 IMP neurological system process
GO:0070852 IEA cell body fiber
GO:0071316 IEA cellular response to nicotine
GO:0071333 IEA cellular response to glucose stimulus
GO:0071356 IEA cellular response to tumor necrosis factor
GO:0071805 IDA potassium ion transmembrane transport
GO:2001259 IEA positive regulation of cation channel activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000031438 kcnj11l potassium inwardly-rectifying channel, subfamily J, member 11, like protein_coding Danio_rerio
ENSMUSG00000096146 Kcnj11 potassium inwardly rectifying channel, subfamily J, member 11 protein_coding Mus_musculus

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