C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: potassium inwardly-rectifying channel, subfamily J, member 11
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000339994 KCNJ11-001 ENSG00000187486 9606 - 11:17385859-17388659 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLungMuscleOvaryPlacentaTestisENST00000339994
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Lung Muscle Ovary Placenta Testis
ENST00000339994 2.870±0.00 0.854±0.00 0.238±0.00 2.137±1.64 0.691±0.66 0.582±0.00 1.884±1.79 0.994±0.00 0.119±0.11 16.091±13.51 0.173±0.04 0.186±0.00 1.077±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003ZU CIL_0003ZU_0001 CGP 11:17385859-17476845

Gene Ontology

GO IDEvidence TypeGO Description
GO:0002931 IEA response to ischemia
GO:0005242 IEA inward rectifier potassium channel activity
GO:0005249 IDA voltage-gated potassium channel activity
GO:0005515 IEA protein binding
GO:0005524 ISS ATP binding
GO:0005635 IEA nuclear envelope
GO:0005739 IEA mitochondrion
GO:0005768 IEA endosome
GO:0005783 IEA endoplasmic reticulum
GO:0005829 IEA cytosol
GO:0005886 IDA plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006006 IMP glucose metabolic process
GO:0006112 TAS energy reserve metabolic process
GO:0006813 IEA potassium ion transport
GO:0007268 TAS synaptic transmission
GO:0008022 IEA protein C-terminus binding
GO:0008076 IDA voltage-gated potassium channel complex
GO:0008282 ISS ATP-sensitive potassium channel complex
GO:0010107 ISS potassium ion import
GO:0014704 IEA intercalated disc
GO:0015272 ISS ATP-activated inward rectifier potassium channel activity
GO:0016021 IEA integral component of membrane
GO:0030315 ISS T-tubule
GO:0030506 IPI ankyrin binding
GO:0030673 IEA axolemma
GO:0030955 TAS potassium ion binding
GO:0031072 IEA heat shock protein binding
GO:0032355 IEA response to estradiol
GO:0033198 IDA response to ATP
GO:0033574 IEA response to testosterone
GO:0042383 IEA sarcolemma
GO:0042391 IDA regulation of membrane potential
GO:0042493 IMP response to drug
GO:0043025 IEA neuronal cell body
GO:0043209 IEA myelin sheath
GO:0043231 IEA intracellular membrane-bounded organelle
GO:0044281 TAS small molecule metabolic process
GO:0044325 IPI ion channel binding
GO:0046676 IMP negative regulation of insulin secretion
GO:0050796 IMP regulation of insulin secretion
GO:0050877 IMP neurological system process
GO:0070852 IEA cell body fiber
GO:0071316 IEA cellular response to nicotine
GO:0071333 IEA cellular response to glucose stimulus
GO:0071356 IEA cellular response to tumor necrosis factor
GO:0071805 IDA potassium ion transmembrane transport
GO:2001259 IEA positive regulation of cation channel activity

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000180081 Kcnj11-201 protein_coding Mus_musculus 0 1480

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