C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: wingless-type MMTV integration site family, member 7B
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000188064 WNT7B 9606 - 22:45920362-45977129 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000339464 WNT7B-001 45920362-45977129 protein_coding
  ENST00000409496 WNT7B-003 45922111-45972715 protein_coding
  ENST00000410058 WNT7B-005 45927482-45976805 protein_coding
  ENST00000410089 WNT7B-002 45922111-45976022 protein_coding
  ENST00000428540 WNT7B-004 45931296-45975909 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000339464ENST00000409496ENST00000410058ENST00000410089
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000339464 0.047±0.00 0.093±0.00 N/A 0.111±0.00 0.215±0.00 0.021±0.00 0.035±0.00 0.630±0.54 0.013±0.00 2.589±0.00 N/A 1.175±0.00 0.814±0.25 0.192±0.00
ENST00000409496 N/A N/A 0.085±0.00 N/A N/A N/A N/A N/A N/A 0.031±0.00 0.432±0.00 0.095±0.00 N/A N/A
ENST00000410058 N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.633±0.00 N/A N/A 0.325±0.00 N/A
ENST00000410089 N/A N/A 0.011±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008KW CIL_0008KW_0001 VISTA 22:45545035-46146420

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001525 IEA angiogenesis
GO:0001701 ISS in utero embryonic development
GO:0001944 IEA vasculature development
GO:0003338 ISS metanephros morphogenesis
GO:0005102 IEA receptor binding
GO:0005109 IBA frizzled binding
GO:0005576 TAS:IEA extracellular region
GO:0005578 IEA proteinaceous extracellular matrix
GO:0005615 IBA extracellular space
GO:0005737 IEA cytoplasm
GO:0005788 TAS endoplasmic reticulum lumen
GO:0005796 TAS Golgi lumen
GO:0005886 TAS plasma membrane
GO:0007257 IEA activation of JUN kinase activity
GO:0007275 IEA multicellular organismal development
GO:0008284 IEA positive regulation of cell proliferation
GO:0010628 IEA positive regulation of gene expression
GO:0016055 ISS:IEA Wnt signaling pathway
GO:0016332 ISS establishment or maintenance of polarity of embryonic epithelium
GO:0021871 IEP forebrain regionalization
GO:0022009 ISS central nervous system vasculogenesis
GO:0030182 IEP neuron differentiation
GO:0030324 ISS lung development
GO:0031175 IEA neuron projection development
GO:0032364 ISS oxygen homeostasis
GO:0032536 IEA regulation of cell projection size
GO:0042475 IEA odontogenesis of dentin-containing tooth
GO:0042592 ISS homeostatic process
GO:0044237 ISS cellular metabolic process
GO:0045165 IBA cell fate commitment
GO:0045669 ISS positive regulation of osteoblast differentiation
GO:0045879 IEA negative regulation of smoothened signaling pathway
GO:0046330 IBA positive regulation of JNK cascade
GO:0048144 IEP fibroblast proliferation
GO:0048568 ISS embryonic organ development
GO:0048812 IEA neuron projection morphogenesis
GO:0050808 ISS synapse organization
GO:0051145 IEA smooth muscle cell differentiation
GO:0051384 IEA response to glucocorticoid
GO:0060033 IEA anatomical structure regression
GO:0060070 ISS canonical Wnt signaling pathway
GO:0060425 ISS lung morphogenesis
GO:0060428 ISS lung epithelium development
GO:0060482 ISS lobar bronchus development
GO:0060484 IEA lung-associated mesenchyme development
GO:0060535 ISS trachea cartilage morphogenesis
GO:0060560 ISS developmental growth involved in morphogenesis
GO:0060669 ISS embryonic placenta morphogenesis
GO:0060710 ISS chorio-allantoic fusion
GO:0061180 IEP mammary gland epithelium development
GO:0070307 ISS lens fiber cell development
GO:0071300 IEP cellular response to retinoic acid
GO:0072053 ISS renal inner medulla development
GO:0072054 ISS renal outer medulla development
GO:0072060 ISS outer medullary collecting duct development
GO:0072061 ISS inner medullary collecting duct development
GO:0072089 IEP stem cell proliferation
GO:0072205 ISS metanephric collecting duct development
GO:0072207 ISS metanephric epithelium development
GO:0072236 ISS metanephric loop of Henle development
GO:1902262 IEA apoptotic process involved in patterning of blood vessels

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000022858 wnt7ba wingless-type MMTV integration site family, member 7Ba protein_coding Danio_rerio
ENSDARG00000071107 wnt7bb wingless-type MMTV integration site family, member 7Bb protein_coding Danio_rerio
ENSMUSG00000022382 Wnt7b wingless-type MMTV integration site family, member 7B protein_coding Mus_musculus

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