C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: wingless-type MMTV integration site family, member 7B
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000022382 Wnt7b 10090 - 15:85535439-85581821 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000023015 Wnt7b-201 85535439-85581821 protein_coding
  ENSMUST00000109424 Wnt7b-202 85535439-85578070 protein_coding
  ENSMUST00000167968 Wnt7b-203 85535439-85580729 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000023015ENSMUST00000109424ENSMUST00000167968
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000023015 1.063±1.02 0.428±0.07 4.377±0.17 10.558±5.90 4.837±1.18 0.059±0.01 0.096±0.06 5.016±0.55 0.085±0.05 4.250±1.08 0.050±0.03 6.413±3.23 9.332±12.32 0.189±0.21
ENSMUST00000109424 N/A N/A N/A 3.275±1.00 N/A N/A N/A N/A 0.028±0.00 N/A N/A 1.762±0.27 N/A N/A
ENSMUST00000167968 N/A N/A N/A N/A N/A 0.034±0.00 N/A N/A 0.017±0.01 N/A 0.035±0.00 0.160±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008KW CIL_0008KW_0002 VISTA 15:85164142-85764949
CIL_000469 CIL_000469_0002 CGP 15:85535439-85802819

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001525 IGI angiogenesis
GO:0001701 IMP in utero embryonic development
GO:0001944 IMP vasculature development
GO:0003338 IMP metanephros morphogenesis
GO:0005102 TAS receptor binding
GO:0005109 IPI frizzled binding
GO:0005578 IEA proteinaceous extracellular matrix
GO:0005615 IBA extracellular space
GO:0005737 IEA cytoplasm
GO:0005788 TAS endoplasmic reticulum lumen
GO:0005886 IEA plasma membrane
GO:0007165 TAS signal transduction
GO:0007257 IEA activation of JUN kinase activity
GO:0007267 TAS cell-cell signaling
GO:0008284 IMP positive regulation of cell proliferation
GO:0009986 IDA cell surface
GO:0010628 IMP positive regulation of gene expression
GO:0016055 IGI Wnt signaling pathway
GO:0016332 IMP establishment or maintenance of polarity of embryonic epithelium
GO:0021846 IDA cell proliferation in forebrain
GO:0021871 IEP forebrain regionalization
GO:0022009 IGI central nervous system vasculogenesis
GO:0030182 IBA neuron differentiation
GO:0030324 IMP lung development
GO:0031175 IEA neuron projection development
GO:0032364 IMP oxygen homeostasis
GO:0032536 IEA regulation of cell projection size
GO:0042475 IMP odontogenesis of dentin-containing tooth
GO:0042592 IMP homeostatic process
GO:0044237 IMP cellular metabolic process
GO:0045165 IBA cell fate commitment
GO:0045669 IDA positive regulation of osteoblast differentiation
GO:0045879 IMP negative regulation of smoothened signaling pathway
GO:0046330 IBA positive regulation of JNK cascade
GO:0048018 IC receptor agonist activity
GO:0048144 IEA fibroblast proliferation
GO:0048568 IMP embryonic organ development
GO:0048812 IEA neuron projection morphogenesis
GO:0048864 IDA stem cell development
GO:0050768 IDA negative regulation of neurogenesis
GO:0050808 IGI synapse organization
GO:0051145 IMP smooth muscle cell differentiation
GO:0051384 IEA response to glucocorticoid
GO:0060033 IMP anatomical structure regression
GO:0060070 IGI canonical Wnt signaling pathway
GO:0060425 IMP lung morphogenesis
GO:0060428 IMP lung epithelium development
GO:0060482 IMP lobar bronchus development
GO:0060484 IMP lung-associated mesenchyme development
GO:0060535 IMP trachea cartilage morphogenesis
GO:0060560 IMP developmental growth involved in morphogenesis
GO:0060669 IMP embryonic placenta morphogenesis
GO:0060710 IMP chorio-allantoic fusion
GO:0061180 IEA mammary gland epithelium development
GO:0071300 IEA cellular response to retinoic acid
GO:0072053 IMP renal inner medulla development
GO:0072054 IMP renal outer medulla development
GO:0072060 IMP outer medullary collecting duct development
GO:0072061 IMP inner medullary collecting duct development
GO:0072089 IEA stem cell proliferation
GO:0072205 IMP metanephric collecting duct development
GO:0072207 IMP metanephric epithelium development
GO:0072236 IMP metanephric loop of Henle development
GO:1902262 IMP apoptotic process involved in patterning of blood vessels

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000022858 wnt7ba wingless-type MMTV integration site family, member 7Ba protein_coding Danio_rerio
ENSDARG00000071107 wnt7bb wingless-type MMTV integration site family, member 7Bb protein_coding Danio_rerio
ENSG00000188064 WNT7B wingless-type MMTV integration site family, member 7B protein_coding Homo_sapiens

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