C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000188488 SERPINA5 9606 + 14:94561442-94593120 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000329597 SERPINA5-201 94581369-94593120 protein_coding
  ENST00000553511 SERPINA5-013 94581426-94587634 protein_coding
  ENST00000553780 SERPINA5-002 94561442-94592796 protein_coding
  ENST00000554220 SERPINA5-001 94561442-94587878 protein_coding
  ENST00000554276 SERPINA5-008 94581615-94593115 protein_coding
  ENST00000554633 SERPINA5-011 94581467-94587620 protein_coding
  ENST00000554760 SERPINA5-012 94581394-94590324 protein_coding
  ENST00000554866 SERPINA5-003 94581394-94593115 protein_coding
  ENST00000555681 SERPINA5-010 94581471-94587795 protein_coding
  ENST00000556064 SERPINA5-015 94581971-94587435 protein_coding
  ENST00000556730 SERPINA5-009 94581391-94590767 retained_intron
  ENST00000556775 SERPINA5-014 94581397-94590115 protein_coding
  ENST00000557598 SERPINA5-016 94581880-94587833 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBladderBreastKidneyLiverMuscleOvaryTestisENST00000329597ENST00000554276ENST00000554760ENST00000554866
Transcript ID Adrenal Bladder Breast Kidney Liver Muscle Ovary Testis
ENST00000329597 N/A N/A N/A 174.755±0.00 N/A N/A 3.304±2.42 46.021±0.00
ENST00000554276 7.232±0.00 N/A N/A N/A 0.540±0.00 N/A 9.401±0.00 73.400±38.67
ENST00000554760 N/A 11.339±0.00 N/A N/A N/A N/A N/A N/A
ENST00000554866 N/A 13.245±0.00 4.944±0.00 76.105±0.00 N/A 0.310±0.00 13.056±6.36 109.912±9.48

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000598 CIL_000598_0008 CGP 14:94487274-94569913
CIL_000598 CIL_000598_0007 CGP 14:94561091-94593120
CIL_000598 CIL_000598_000C CGP 14:94561442-94624646

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001972 IDA retinoic acid binding
GO:0002020 IPI protease binding
GO:0002080 IDA acrosomal membrane
GO:0004867 IDA serine-type endopeptidase inhibitor activity
GO:0005515 IEA protein binding
GO:0005539 TAS glycosaminoglycan binding
GO:0005576 IBA extracellular region
GO:0005615 IEA:IDA extracellular space
GO:0006869 IEA lipid transport
GO:0007283 ISS spermatogenesis
GO:0007342 NAS fusion of sperm to egg plasma membrane
GO:0008201 TAS heparin binding
GO:0009897 IDA external side of plasma membrane
GO:0010951 IBA negative regulation of endopeptidase activity
GO:0016020 IDA membrane
GO:0030162 IBA regulation of proteolysis
GO:0031091 IDA platelet alpha granule
GO:0031094 IDA platelet dense tubular network
GO:0031210 IDA phosphatidylcholine binding
GO:0032190 IPI acrosin binding
GO:0036024 IDA protein C inhibitor-TMPRSS7 complex
GO:0036025 IDA protein C inhibitor-TMPRSS11E complex
GO:0036026 IDA protein C inhibitor-PLAT complex
GO:0036027 IDA protein C inhibitor-PLAU complex
GO:0036028 IDA protein C inhibitor-thrombin complex
GO:0036029 IDA protein C inhibitor-KLK3 complex
GO:0036030 IDA protein C inhibitor-plasma kallikrein complex
GO:0043234 IDA protein complex
GO:0045861 IEA negative regulation of proteolysis
GO:0070062 IDA extracellular vesicular exosome
GO:0097181 IDA protein C inhibitor-coagulation factor V complex
GO:0097182 IDA protein C inhibitor-coagulation factor Xa complex
GO:0097183 IDA protein C inhibitor-coagulation factor XI complex

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000074712 si:ch211-186e20.2 si:ch211-186e20.2 protein_coding Danio_rerio
ENSDARG00000077960 si:ch211-186e20.7 si:ch211-186e20.7 protein_coding Danio_rerio
ENSDARG00000087143 serpina7 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 protein_coding Danio_rerio
ENSDARG00000090286 serpina1 serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 protein_coding Danio_rerio
ENSDARG00000090850 serpina1l serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1, like protein_coding Danio_rerio
ENSDARG00000090916 CR559930.2 Uncharacterized protein protein_coding Danio_rerio
ENSDARG00000091136 zgc:174259 zgc:174259 protein_coding Danio_rerio
ENSDARG00000091800 zgc:174260 zgc:174260 protein_coding Danio_rerio
ENSMUSG00000041550 Serpina5 serine (or cysteine) peptidase inhibitor, clade A, member 5 protein_coding Mus_musculus

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