C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: serine (or cysteine) peptidase inhibitor, clade A, member 5
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000041550 Serpina5 10090 + 12:104101113-104106137 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000021495 Serpina5-001 104101113-104106137 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalHeartLiverLungMuscleOvaryPlacentaTestisENSMUST00000021495
Transcript ID Adipose Adrenal Heart Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000021495 0.051±0.02 0.039±0.00 0.012±0.00 0.579±1.34 0.017±0.00 0.034±0.01 37.656±10.70 0.754±0.58 19.484±3.98

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000598 CIL_000598_000J CGP 12:104028769-104106137
CIL_000598 CIL_000598_000I CGP 12:104101113-104121896

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001972 ISS retinoic acid binding
GO:0002020 IEA protease binding
GO:0002080 ISS acrosomal membrane
GO:0004867 ISS serine-type endopeptidase inhibitor activity
GO:0005515 IPI protein binding
GO:0005576 IBA extracellular region
GO:0005615 ISS extracellular space
GO:0007283 IMP spermatogenesis
GO:0009897 IEA external side of plasma membrane
GO:0010951 IBA negative regulation of endopeptidase activity
GO:0016020 IEA membrane
GO:0030162 IBA regulation of proteolysis
GO:0031091 ISS platelet alpha granule
GO:0031094 ISS platelet dense tubular network
GO:0031210 ISS phosphatidylcholine binding
GO:0032190 IEA acrosin binding
GO:0036024 ISS protein C inhibitor-TMPRSS7 complex
GO:0036025 ISS protein C inhibitor-TMPRSS11E complex
GO:0036026 ISS protein C inhibitor-PLAT complex
GO:0036027 ISS protein C inhibitor-PLAU complex
GO:0036028 ISS protein C inhibitor-thrombin complex
GO:0036029 ISS protein C inhibitor-KLK3 complex
GO:0036030 ISS protein C inhibitor-plasma kallikrein complex
GO:0043234 IEA protein complex
GO:0045861 IEA negative regulation of proteolysis
GO:0070062 IEA extracellular vesicular exosome
GO:0097181 ISS protein C inhibitor-coagulation factor V complex
GO:0097182 ISS protein C inhibitor-coagulation factor Xa complex
GO:0097183 ISS protein C inhibitor-coagulation factor XI complex

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000074712 si:ch211-186e20.2 si:ch211-186e20.2 protein_coding Danio_rerio
ENSDARG00000077960 si:ch211-186e20.7 si:ch211-186e20.7 protein_coding Danio_rerio
ENSDARG00000087143 serpina7 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 7 protein_coding Danio_rerio
ENSDARG00000090286 serpina1 serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1 protein_coding Danio_rerio
ENSDARG00000090850 serpina1l serine (or cysteine) proteinase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 1, like protein_coding Danio_rerio
ENSDARG00000090916 CR559930.2 Uncharacterized protein protein_coding Danio_rerio
ENSDARG00000091136 zgc:174259 zgc:174259 protein_coding Danio_rerio
ENSDARG00000091800 zgc:174260 zgc:174260 protein_coding Danio_rerio
ENSG00000188488 SERPINA5 serpin peptidase inhibitor, clade A (alpha-1 antiproteinase, antitrypsin), member 5 protein_coding Homo_sapiens

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