C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: adrenoceptor beta 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000188778 ADRB3 9606 - 8:37962991-37966965 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000345060 ADRB3-001 37962991-37966965 protein_coding
  ENST00000520341 ADRB3-003 37963962-37965744 processed_transcript
  ENST00000614635 ADRB3-201 37963000-37966666 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000345060ENST00000520341ENST00000614635
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000345060 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.357±0.00 N/A
ENST00000520341 N/A 0.019±0.00 N/A N/A N/A 0.111±0.00 0.248±0.00 N/A N/A N/A N/A 4.172±0.00 0.152±0.00
ENST00000614635 0.082±0.00 0.024±0.00 0.156±0.00 0.361±0.00 0.372±0.31 0.011±0.00 0.063±0.00 0.044±0.04 0.017±0.00 0.008±0.00 7.407±6.34 2.559±0.10 0.222±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0009C5 CIL_0009C5_0001 VISTA 8:37525567-38127835
CIL_0007QT CIL_0007QT_0001 VISTA 8:37525572-38127829
CIL_00009T CIL_00009T_0001 CGP 8:37934281-37966965
CIL_0002IS CIL_0002IS_0001 CGP 8:37962991-38060365

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002024 IEA diet induced thermogenesis
GO:0002025 IEA vasodilation by norepinephrine-epinephrine involved in regulation of systemic arterial blood pressure
GO:0004930 IEA G-protein coupled receptor activity
GO:0004939 IDA beta-adrenergic receptor activity
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005886 TAS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0005975 TAS carbohydrate metabolic process
GO:0006091 TAS generation of precursor metabolites and energy
GO:0006112 TAS energy reserve metabolic process
GO:0007186 IEA G-protein coupled receptor signaling pathway
GO:0007187 TAS G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger
GO:0007188 TAS adenylate cyclase-modulating G-protein coupled receptor signaling pathway
GO:0007189 IEA adenylate cyclase-activating G-protein coupled receptor signaling pathway
GO:0007190 IDA activation of adenylate cyclase activity
GO:0007568 IEA aging
GO:0009409 IEA response to cold
GO:0015052 IMP beta3-adrenergic receptor activity
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0031649 IEA heat generation
GO:0031699 IEA beta-3 adrenergic receptor binding
GO:0040015 IEA negative regulation of multicellular organism growth
GO:0042755 IEA eating behavior
GO:0042803 IDA protein homodimerization activity
GO:0043235 IDA receptor complex
GO:0043410 IDA positive regulation of MAPK cascade
GO:0046677 IEA response to antibiotic
GO:0050873 IEA brown fat cell differentiation
GO:0051379 IEA epinephrine binding
GO:0051380 IDA norepinephrine binding
GO:0071875 IEA adrenergic receptor signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000052919 adrb3b adrenergic receptor, beta 3b protein_coding Danio_rerio
ENSDARG00000053646 adrb3a adrenergic receptor, beta 3a protein_coding Danio_rerio
ENSMUSG00000031489 Adrb3 adrenergic receptor, beta 3 protein_coding Mus_musculus

Loading