C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: metal-regulatory transcription factor 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000188786 MTF1 9606 - 1:37809567-37859620 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000373036 MTF1-001 37809567-37859620 protein_coding
  ENST00000468190 MTF1-002 37857349-37858539 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000373036ENST00000468190
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000373036 2.313±0.00 1.617±0.00 1.053±0.00 0.938±0.50 1.302±0.02 1.209±0.56 0.635±0.32 1.552±0.65 0.800±0.04 1.546±0.41 1.797±0.00 1.973±1.13 1.205±0.51 4.615±0.53
ENST00000468190 N/A N/A 3.764±0.00 N/A 6.703±0.00 N/A N/A N/A 4.072±0.00 4.614±0.00 3.019±0.00 N/A N/A 8.689±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00095Y CIL_00095Y_0001 VISTA 1:37729017-38330016
CIL_0007UI CIL_0007UI_0001 VISTA 1:37794522-38395934

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000978 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000979 IEA RNA polymerase II core promoter sequence-specific DNA binding
GO:0001047 IDA core promoter binding
GO:0001077 IDA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003677 TAS DNA binding
GO:0003700 TAS sequence-specific DNA binding transcription factor activity
GO:0003713 TAS transcription coactivator activity
GO:0005515 IPI protein binding
GO:0005634 IDA nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0006357 TAS regulation of transcription from RNA polymerase II promoter
GO:0006979 IEA response to oxidative stress
GO:0010038 TAS response to metal ion
GO:0035035 IEA histone acetyltransferase binding
GO:0045893 IEA positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046686 IEA response to cadmium ion
GO:0046872 IEA metal ion binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000090180 mtf1 metal-regulatory transcription factor 1 protein_coding Danio_rerio
ENSMUSG00000028890 Mtf1 metal response element binding transcription factor 1 protein_coding Mus_musculus

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