C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: metal response element binding transcription factor 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000028890 Mtf1 10090 + 4:124802104-124849800 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000030723 Mtf1-201 124802549-124849800 protein_coding
  ENSMUST00000106193 Mtf1-001 124802104-124849379 protein_coding
  ENSMUST00000138807 Mtf1-002 124802549-124820227 protein_coding
  ENSMUST00000147452 Mtf1-003 124802582-124805378 retained_intron
  ENSMUST00000175875 Mtf1-004 124802678-124804740 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000030723ENSMUST00000106193ENSMUST00000138807
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000030723 2.944±0.98 7.180±1.88 N/A N/A 5.834±1.69 5.727±1.15 2.853±0.00 3.424±1.06 3.413±0.63 4.797±0.64 N/A 7.896±1.74 N/A 21.293±0.56
ENSMUST00000106193 2.113±0.65 N/A 3.696±0.35 3.889±0.25 3.116±0.60 N/A 2.405±0.28 3.782±0.00 3.413±1.09 N/A 2.528±0.59 3.546±0.10 5.905±2.04 8.129±1.21
ENSMUST00000138807 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 96.302±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000892 CIL_000892_0002 VISTA 4:124220131-124821365
CIL_0008EP CIL_0008EP_0002 VISTA 4:124226300-124827138
CIL_0008NZ CIL_0008NZ_0002 VISTA 4:124251046-124852185
CIL_0007UI CIL_0007UI_0002 VISTA 4:124315408-124916812
CIL_00095Y CIL_00095Y_0002 VISTA 4:124371949-124972943
CIL_0002SC CIL_0002SC_0002 CGP 4:124741850-124849800

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000978 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding
GO:0000979 IDA RNA polymerase II core promoter sequence-specific DNA binding
GO:0001047 IEA core promoter binding
GO:0001077 IEA RNA polymerase II core promoter proximal region sequence-specific DNA binding transcription factor activity involved in positive regulation of transcription
GO:0003677 IDA DNA binding
GO:0003700 IDA sequence-specific DNA binding transcription factor activity
GO:0005515 IEA protein binding
GO:0005634 IC nucleus
GO:0006351 IEA transcription, DNA-templated
GO:0006979 IMP response to oxidative stress
GO:0035035 IPI histone acetyltransferase binding
GO:0045893 IMP positive regulation of transcription, DNA-templated
GO:0045944 IDA positive regulation of transcription from RNA polymerase II promoter
GO:0046686 IMP response to cadmium ion
GO:0046872 IEA metal ion binding

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000090180 mtf1 metal-regulatory transcription factor 1 protein_coding Danio_rerio
ENSG00000188786 MTF1 metal-regulatory transcription factor 1 protein_coding Homo_sapiens

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