C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: isoleucyl-tRNA synthetase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000196305 IARS 9606 - 9:92210207-92293716 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000375627 IARS-010 92229001-92245101 protein_coding
  ENST00000375643 IARS-001 92210207-92293700 protein_coding
  ENST00000395554 IARS-002 92274426-92293716 protein_coding
  ENST00000430417 IARS-006 92287824-92293641 protein_coding
  ENST00000443024 IARS-201 92210345-92293694 protein_coding
  ENST00000447699 IARS-202 92210345-92293695 protein_coding
  ENST00000467876 IARS-013 92250190-92250910 processed_transcript
  ENST00000472894 IARS-009 92256357-92260212 processed_transcript
  ENST00000473915 IARS-011 92240763-92243449 processed_transcript
  ENST00000474340 IARS-012 92240289-92243228 processed_transcript
  ENST00000490438 IARS-007 92287413-92293716 processed_transcript
  ENST00000498025 IARS-008 92277863-92286131 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000375643ENST00000443024ENST00000447699
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000375643 1.577±0.00 N/A N/A 2.482±0.00 2.377±0.62 1.930±0.19 1.515±0.00 0.710±0.00 1.330±0.01 N/A N/A 4.672±0.57 2.873±0.00 N/A
ENST00000443024 7.934±0.00 7.981±0.00 4.303±0.00 10.634±1.56 4.749±1.54 5.838±0.58 7.257±3.44 6.772±4.38 5.028±1.65 4.172±0.76 20.129±13.44 21.726±12.08 12.143±4.88 11.035±1.38
ENST00000447699 3.399±0.00 8.459±0.00 N/A N/A 6.147±0.00 3.974±0.00 N/A 7.412±0.00 4.419±0.00 2.998±0.00 7.185±0.00 3.850±0.00 N/A 3.581±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000166 IEA nucleotide binding
GO:0001649 IDA osteoblast differentiation
GO:0002161 IEA aminoacyl-tRNA editing activity
GO:0004812 IEA aminoacyl-tRNA ligase activity
GO:0004822 IEA:TAS isoleucine-tRNA ligase activity
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005737 IEA:TAS cytoplasm
GO:0005829 TAS cytosol
GO:0006418 IEA:TAS tRNA aminoacylation for protein translation
GO:0006428 IEA isoleucyl-tRNA aminoacylation
GO:0006450 IEA regulation of translational fidelity
GO:0010467 TAS gene expression
GO:0016020 IDA membrane
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000007955 iars isoleucyl-tRNA synthetase protein_coding Danio_rerio
ENSMUSG00000037851 Iars isoleucine-tRNA synthetase protein_coding Mus_musculus

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