C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: isoleucine-tRNA synthetase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000037851 Iars 10090 + 13:49682100-49734267 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000047363 Iars-201 49682130-49734267 protein_coding
  ENSMUST00000164260 Iars-202 49687393-49733741 protein_coding
  ENSMUST00000164275 Iars-005 49708216-49715156 retained_intron
  ENSMUST00000165063 Iars-004 49706557-49715782 retained_intron
  ENSMUST00000165270 Iars-007 49717856-49723168 retained_intron
  ENSMUST00000165316 Iars-001 49682100-49734267 protein_coding
  ENSMUST00000165656 Iars-006 49722119-49723096 retained_intron
  ENSMUST00000171510 Iars-003 49705806-49711781 nonsense_mediated_decay
  ENSMUST00000172254 Iars-002 49682191-49688313 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000047363ENSMUST00000164260ENSMUST00000165316
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000047363 12.258±5.64 6.575±2.73 15.974±0.06 14.273±1.84 8.019±1.75 7.017±1.04 11.382±1.02 10.101±0.28 18.811±11.72 9.506±1.44 17.038±1.11 15.816±4.70 22.816±10.37 7.767±2.55
ENSMUST00000164260 N/A N/A N/A N/A N/A 2.141±0.00 N/A N/A N/A N/A N/A 2.984±0.00 N/A N/A
ENSMUST00000165316 N/A N/A N/A N/A N/A N/A N/A N/A 1.722±0.00 N/A N/A N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001649 IEA osteoblast differentiation
GO:0002161 IEA aminoacyl-tRNA editing activity
GO:0004812 IEA aminoacyl-tRNA ligase activity
GO:0004822 IEA isoleucine-tRNA ligase activity
GO:0005515 IEA protein binding
GO:0005524 IEA ATP binding
GO:0005737 IEA cytoplasm
GO:0006418 IEA tRNA aminoacylation for protein translation
GO:0006428 IEA isoleucyl-tRNA aminoacylation
GO:0006450 IEA regulation of translational fidelity
GO:0016020 IEA membrane
GO:0070062 IEA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000007955 iars isoleucyl-tRNA synthetase protein_coding Danio_rerio
ENSG00000196305 IARS isoleucyl-tRNA synthetase protein_coding Homo_sapiens

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