C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: nascent polypeptide-associated complex alpha subunit
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000196531 NACA 9606 - 12:56712428-56731628 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000356769 NACA-001 56712433-56727197 protein_coding
  ENST00000393891 NACA-003 56712435-56725267 protein_coding
  ENST00000454682 NACA-201 56712428-56725542 protein_coding
  ENST00000546392 NACA-005 56712504-56725354 protein_coding
  ENST00000546410 NACA-017 56712644-56713396 retained_intron
  ENST00000546862 NACA-012 56713121-56725285 protein_coding
  ENST00000546917 NACA-006 56724505-56725516 protein_coding
  ENST00000547914 NACA-015 56712536-56725298 nonsense_mediated_decay
  ENST00000548084 NACA-013 56714381-56725270 nonsense_mediated_decay
  ENST00000548386 NACA-016 56712440-56713582 processed_transcript
  ENST00000548563 NACA-011 56712440-56725299 protein_coding
  ENST00000549259 NACA-007 56712825-56724919 protein_coding
  ENST00000549855 NACA-020 56713539-56731628 protein_coding
  ENST00000550343 NACA-019 56714253-56714757 processed_transcript
  ENST00000550920 NACA-018 56712428-56719600 protein_coding
  ENST00000550952 NACA-004 56712433-56725299 protein_coding
  ENST00000551520 NACA-009 56714249-56725295 retained_intron
  ENST00000551775 NACA-010 56713064-56725304 processed_transcript
  ENST00000551793 NACA-008 56713869-56725301 processed_transcript
  ENST00000552055 NACA-014 56713116-56725036 protein_coding
  ENST00000552540 NACA-002 56712435-56725256 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000393891ENST00000454682ENST00000546392ENST00000546862ENST00000547914ENST00000549259ENST00000549855ENST00000550920ENST00000550952ENST00000551775
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000393891 N/A N/A N/A 57.973±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 70.452±0.20 N/A
ENST00000454682 N/A N/A N/A N/A N/A N/A 99.359±0.00 N/A N/A N/A 170.396±164.78 N/A N/A N/A
ENST00000546392 160.158±0.00 141.295±0.00 N/A 60.620±11.88 105.790±50.71 123.034±94.73 18.127±0.00 167.594±0.00 122.201±72.28 165.451±130.87 N/A 687.043±342.84 173.550±106.04 193.648±7.94
ENST00000546862 209.745±0.00 240.935±0.00 N/A 105.306±0.00 209.787±0.00 321.839±0.00 N/A N/A N/A 199.989±0.00 N/A N/A N/A 213.664±0.00
ENST00000547914 N/A N/A N/A N/A 42.921±0.00 29.122±0.00 N/A N/A N/A N/A N/A 1922.210±0.00 647.552±0.00 412.810±0.00
ENST00000549259 N/A N/A 26.810±0.00 32.953±0.00 N/A 40.800±0.00 20.603±0.00 N/A 50.670±0.00 60.120±0.00 N/A N/A N/A N/A
ENST00000549855 N/A N/A 21.340±0.00 60.978±0.00 72.401±0.00 46.528±0.00 32.428±0.00 N/A 80.855±0.00 62.446±0.00 N/A 234.471±0.00 N/A N/A
ENST00000550920 155.140±0.00 206.840±0.00 15.414±0.00 40.059±4.22 71.213±41.98 103.413±78.86 N/A 96.864±0.00 49.326±0.00 33.167±0.00 N/A 615.917±0.00 136.651±27.00 156.541±0.00
ENST00000550952 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 22.177±0.00 N/A N/A N/A
ENST00000551775 N/A N/A N/A N/A N/A N/A N/A N/A N/A 254.228±0.00 N/A N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003231 ISS cardiac ventricle development
GO:0003677 IEA DNA binding
GO:0003713 ISS transcription coactivator activity
GO:0005515 IPI:IEA protein binding
GO:0005634 ISS nucleus
GO:0005737 ISS cytoplasm
GO:0005854 TAS nascent polypeptide-associated complex
GO:0006351 IEA transcription, DNA-templated
GO:0006355 IEA regulation of transcription, DNA-templated
GO:0006412 TAS translation
GO:0010664 ISS negative regulation of striated muscle cell apoptotic process
GO:0015031 IEA protein transport
GO:0016032 IEA viral process
GO:0017025 ISS TBP-class protein binding
GO:0043403 ISS skeletal muscle tissue regeneration
GO:0048633 ISS positive regulation of skeletal muscle tissue growth
GO:0048742 ISS regulation of skeletal muscle fiber development
GO:0061384 ISS heart trabecula morphogenesis
GO:0070062 IDA extracellular vesicular exosome
GO:1901227 ISS negative regulation of transcription from RNA polymerase II promoter involved in heart development
GO:1901228 ISS positive regulation of transcription from RNA polymerase II promoter involved in heart development
GO:2000138 ISS positive regulation of cell proliferation involved in heart morphogenesis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000061315 Naca nascent polypeptide-associated complex alpha polypeptide protein_coding Mus_musculus

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