C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: WNK lysine deficient protein kinase 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000196632 WNK3 9606 - X:54192823-54358642 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000354646 WNK3-201 54192825-54358005 protein_coding
  ENST00000375159 WNK3-002 54198324-54333673 protein_coding
  ENST00000375169 WNK3-001 54192823-54358005 protein_coding
  ENST00000458404 WNK3-003 54333178-54358642 protein_coding
  ENST00000620763 WNK3-202 54198324-54333673 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000354646ENST00000375159ENST00000375169ENST00000620763
Transcript ID Adipose Adrenal Bladder Brain Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000354646 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.362±0.00
ENST00000375159 0.070±0.00 N/A N/A N/A 0.017±0.00 N/A 0.233±0.00 N/A N/A N/A 0.023±0.00 N/A
ENST00000375169 N/A 0.050±0.00 0.454±0.00 0.514±0.00 0.138±0.00 1.018±0.37 1.324±0.00 N/A 0.001±0.00 0.338±0.28 0.052±0.00 1.762±0.76
ENST00000620763 N/A N/A 0.190±0.00 N/A 0.015±0.00 0.493±0.00 N/A 0.068±0.00 N/A N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004672 IDA:IEA protein kinase activity
GO:0004674 ISS:IEA protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 ISS:IEA ATP binding
GO:0005737 IDA cytoplasm
GO:0005912 ISS adherens junction
GO:0005923 ISS tight junction
GO:0006468 ISS:IEA protein phosphorylation
GO:0010765 IDA positive regulation of sodium ion transport
GO:0010800 IDA positive regulation of peptidyl-threonine phosphorylation
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0019869 IDA chloride channel inhibitor activity
GO:0032414 IDA positive regulation of ion transmembrane transporter activity
GO:0035556 ISS intracellular signal transduction
GO:0043066 IMP negative regulation of apoptotic process
GO:0046777 IDA protein autophosphorylation
GO:0051928 IMP positive regulation of calcium ion transport
GO:0090004 IDA positive regulation of establishment of protein localization to plasma membrane
GO:2000021 IMP regulation of ion homeostasis
GO:2000651 IDA positive regulation of sodium ion transmembrane transporter activity
GO:2000682 IDA positive regulation of rubidium ion transport
GO:2000688 IDA positive regulation of rubidium ion transmembrane transporter activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000041245 Wnk3 WNK lysine deficient protein kinase 3 protein_coding Mus_musculus

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