C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Transcript Info
Description: WNK lysine deficient protein kinase 3
Transcript Accession Transcript Name Contained in Gene Tax ID Strand Position Biotype
ENST00000375159 WNK3-002 ENSG00000196632 9606 - X:54198324-54333673 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeHeartLiverPlacentaENST00000375159
Transcript ID Adipose Heart Liver Placenta
ENST00000375159 0.070±0.00 0.017±0.00 0.233±0.00 0.023±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004672 IDA:IEA protein kinase activity
GO:0004674 ISS:IEA protein serine/threonine kinase activity
GO:0004713 IEA protein tyrosine kinase activity
GO:0005515 IPI protein binding
GO:0005524 ISS:IEA ATP binding
GO:0005737 IDA cytoplasm
GO:0005912 ISS adherens junction
GO:0005923 ISS tight junction
GO:0006468 ISS:IEA protein phosphorylation
GO:0010765 IDA positive regulation of sodium ion transport
GO:0010800 IDA positive regulation of peptidyl-threonine phosphorylation
GO:0016772 IEA transferase activity, transferring phosphorus-containing groups
GO:0019869 IDA chloride channel inhibitor activity
GO:0032414 IDA positive regulation of ion transmembrane transporter activity
GO:0035556 ISS intracellular signal transduction
GO:0043066 IMP negative regulation of apoptotic process
GO:0046777 IDA protein autophosphorylation
GO:0051928 IMP positive regulation of calcium ion transport
GO:0090004 IDA positive regulation of establishment of protein localization to plasma membrane
GO:2000021 IMP regulation of ion homeostasis
GO:2000651 IDA positive regulation of sodium ion transmembrane transporter activity
GO:2000682 IDA positive regulation of rubidium ion transport
GO:2000688 IDA positive regulation of rubidium ion transmembrane transporter activity

Homologs

ENSEMBL Accession Gene Name Biotype Species E-Value Bit Score
ENSMUST00000149140 Wnk3-002 nonsense_mediated_decay Mus_musculus 0 5188
ENSMUST00000096285 Wnk3-201 protein_coding Mus_musculus 0 5169
ENSMUST00000184392 Wnk3-005 protein_coding Mus_musculus 0 3014
ENSMUST00000184730 Wnk3-004 protein_coding Mus_musculus 0 2161
ENSMUST00000131844 Wnk3-003 processed_transcript Mus_musculus 0 712
ENSMUST00000133852 Wnk3-001 processed_transcript Mus_musculus 0 628
ENSDART00000035702 protein_coding Danio_rerio 2e-31 143

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