C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: KN motif and ankyrin repeat domains 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000197256 KANK2 9606 - 19:11164267-11197791 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000586659 KANK2-001 11164267-11197521 protein_coding
  ENST00000587317 KANK2-013 11166309-11170415 processed_transcript
  ENST00000588724 KANK2-007 11193946-11197548 protein_coding
  ENST00000588787 KANK2-005 11164270-11175947 protein_coding
  ENST00000589359 KANK2-003 11166558-11197547 protein_coding
  ENST00000589427 KANK2-014 11196058-11197183 retained_intron
  ENST00000589894 KANK2-015 11169676-11194511 protein_coding
  ENST00000590095 KANK2-009 11195623-11196227 processed_transcript
  ENST00000590400 KANK2-006 11192432-11197791 retained_intron
  ENST00000590685 KANK2-012 11193637-11195192 protein_coding
  ENST00000592215 KANK2-010 11194553-11196229 processed_transcript
  ENST00000592675 KANK2-008 11192881-11195685 protein_coding
  ENST00000592903 KANK2-011 11194504-11197530 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000586659ENST00000588787ENST00000589894
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000586659 22.965±0.00 21.133±0.00 2.736±0.00 2.668±0.00 20.766±0.00 46.320±0.00 25.987±23.00 6.756±4.48 4.936±0.31 16.453±13.16 4.016±0.00 51.488±57.57 12.985±2.95 17.356±14.07
ENST00000588787 9.825±0.00 26.715±0.00 N/A 0.270±0.00 30.891±0.00 78.361±0.00 23.243±0.00 12.562±0.00 5.653±0.00 20.653±0.00 4.219±0.00 10.012±4.48 10.775±2.03 23.887±17.83
ENST00000589894 N/A N/A N/A 0.290±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000167 CIL_000167_0001 CGP 19:11131520-11197791
CIL_0001EZ CIL_0001EZ_0002 CGP 19:11164267-11262481

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000122 IDA negative regulation of transcription from RNA polymerase II promoter
GO:0005515 IPI:IEA protein binding
GO:0005737 IDA cytoplasm
GO:0005739 IDA mitochondrion
GO:0006351 IEA transcription, DNA-templated
GO:0006915 IEA apoptotic process
GO:0008285 IDA negative regulation of cell proliferation
GO:0033147 IDA negative regulation of intracellular estrogen receptor signaling pathway
GO:0043069 IDA negative regulation of programmed cell death
GO:2000134 IDA negative regulation of G1/S transition of mitotic cell cycle

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000018393 kank2 KN motif and ankyrin repeat domains 2 protein_coding Danio_rerio
ENSMUSG00000032194 Kank2 KN motif and ankyrin repeat domains 2 protein_coding Mus_musculus

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