C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: complement component 5a receptor 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000197405 C5AR1 9606 + 19:47290023-47322066 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000355085 C5AR1-003 47309874-47322066 protein_coding
  ENST00000594787 C5AR1-002 47297075-47320186 protein_coding
  ENST00000595501 C5AR1-001 47290023-47307754 processed_transcript

Homo sapiens EnsemblGRCh38

Genome
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Genes
Gene structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000355085ENST00000594787
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000355085 28.288±0.00 2.248±0.00 1.307±1.01 3.476±1.70 3.306±2.76 1.351±1.32 3.953±3.81 2.019±1.28 14.730±11.90 0.553±0.51 3.167±1.99 8.908±3.03 2.778±0.00
ENST00000594787 N/A N/A N/A N/A N/A N/A 0.294±0.00 N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008G1 CIL_0008G1_0001 VISTA 19:46806794-47408636

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000187 TAS activation of MAPK activity
GO:0001856 IEA complement component C5a binding
GO:0002430 IEA complement receptor mediated signaling pathway
GO:0004878 IDA complement component C5a receptor activity
GO:0004930 IEA G-protein coupled receptor activity
GO:0004944 IDA C5a anaphylatoxin receptor activity
GO:0005886 TAS plasma membrane
GO:0005887 TAS integral component of plasma membrane
GO:0006915 IEA apoptotic process
GO:0006935 TAS chemotaxis
GO:0006954 IEA inflammatory response
GO:0006955 TAS immune response
GO:0006968 TAS cellular defense response
GO:0007165 TAS signal transduction
GO:0007186 IEA G-protein coupled receptor signaling pathway
GO:0007202 TAS activation of phospholipase C activity
GO:0007204 IEA positive regulation of cytosolic calcium ion concentration
GO:0007606 TAS sensory perception of chemical stimulus
GO:0009986 IEA cell surface
GO:0016021 IEA integral component of membrane
GO:0016323 IDA basolateral plasma membrane
GO:0021534 IEA cell proliferation in hindbrain
GO:0030593 IEA neutrophil chemotaxis
GO:0031100 IEA organ regeneration
GO:0032494 IEA response to peptidoglycan
GO:0032496 IEA response to lipopolysaccharide
GO:0038178 IDA complement component C5a signaling pathway
GO:0042789 IDA mRNA transcription from RNA polymerase II promoter
GO:0043524 IEA negative regulation of neuron apoptotic process
GO:0045177 IDA apical part of cell
GO:0050679 IDA positive regulation of epithelial cell proliferation
GO:0050830 IEA defense response to Gram-positive bacterium
GO:0070374 IDA positive regulation of ERK1 and ERK2 cascade

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000040319 C5AR1 C5a anaphylatoxin chemotactic receptor 1 protein_coding Danio_rerio
ENSMUSG00000049130 C5ar1 complement component 5a receptor 1 protein_coding Mus_musculus

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