C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: complement component 5a receptor 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000049130 C5ar1 10090 - 7:16246743-16259540 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000050770 C5ar1-201 16246743-16259540 protein_coding
  ENSMUST00000168818 C5ar1-202 16246745-16259338 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000050770ENSMUST00000168818
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000050770 5.783±1.11 2.899±0.77 4.329±1.22 0.240±0.17 7.691±3.19 5.859±1.14 2.310±1.17 1.115±0.20 1.628±1.90 13.629±1.73 0.295±0.09 4.575±2.31 0.653±0.81 0.157±0.10
ENSMUST00000168818 3.954±0.98 1.682±0.79 1.909±0.57 0.114±0.00 3.999±1.95 1.174±0.44 1.380±0.07 0.395±0.00 0.489±0.29 1.847±0.55 N/A 1.607±0.81 0.336±0.27 0.183±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008G1 CIL_0008G1_0002 VISTA 7:16104746-16706411

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001856 IEA complement component C5a binding
GO:0002430 IEA complement receptor mediated signaling pathway
GO:0004878 IEA complement component C5a receptor activity
GO:0004944 IDA C5a anaphylatoxin receptor activity
GO:0005886 IEA plasma membrane
GO:0006915 IEA apoptotic process
GO:0006954 IEA inflammatory response
GO:0007204 IEA positive regulation of cytosolic calcium ion concentration
GO:0009986 IEA cell surface
GO:0016021 IEA integral component of membrane
GO:0016323 IEA basolateral plasma membrane
GO:0021534 IEA cell proliferation in hindbrain
GO:0030593 IMP neutrophil chemotaxis
GO:0031100 IEA organ regeneration
GO:0032494 IMP response to peptidoglycan
GO:0032496 IEA response to lipopolysaccharide
GO:0038178 IEA complement component C5a signaling pathway
GO:0042789 IEA mRNA transcription from RNA polymerase II promoter
GO:0043524 IEA negative regulation of neuron apoptotic process
GO:0045177 IEA apical part of cell
GO:0050679 IEA positive regulation of epithelial cell proliferation
GO:0050830 IMP defense response to Gram-positive bacterium
GO:0070374 IEA positive regulation of ERK1 and ERK2 cascade

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000040319 C5AR1 C5a anaphylatoxin chemotactic receptor 1 protein_coding Danio_rerio
ENSG00000197405 C5AR1 complement component 5a receptor 1 protein_coding Homo_sapiens

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