C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: signal-induced proliferation-associated 1 like 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000197555 SIPA1L1 9606 + 14:71320449-71741229 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000358550 SIPA1L1-001 71586281-71739401 protein_coding
  ENST00000381232 SIPA1L1-003 71529325-71739405 protein_coding
  ENST00000537413 SIPA1L1-019 71598234-71739341 protein_coding
  ENST00000553453 SIPA1L1-015 71320449-71529370 processed_transcript
  ENST00000554126 SIPA1L1-009 71320476-71573513 processed_transcript
  ENST00000554362 SIPA1L1-014 71320476-71587694 processed_transcript
  ENST00000554874 SIPA1L1-005 71702312-71739367 processed_transcript
  ENST00000554960 SIPA1L1-004 71685362-71709342 retained_intron
  ENST00000555066 SIPA1L1-006 71618756-71661449 protein_coding
  ENST00000555652 SIPA1L1-016 71320515-71587622 processed_transcript
  ENST00000555818 SIPA1L1-002 71529325-71741229 protein_coding
  ENST00000555989 SIPA1L1-008 71320449-71587765 processed_transcript
  ENST00000556408 SIPA1L1-013 71320473-71573800 processed_transcript
  ENST00000556780 SIPA1L1-012 71320476-71573653 processed_transcript
  ENST00000556959 SIPA1L1-007 71730192-71735593 retained_intron
  ENST00000557151 SIPA1L1-010 71321391-71587969 protein_coding
  ENST00000557469 SIPA1L1-011 71413954-71416283 processed_transcript
  ENST00000557712 SIPA1L1-017 71467185-71575086 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000358550ENST00000381232ENST00000537413ENST00000554874ENST00000555652ENST00000555818
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000358550 N/A N/A N/A 3.157±0.00 N/A N/A 0.105±0.00 N/A N/A N/A N/A 0.760±0.00 N/A N/A
ENST00000381232 1.576±0.00 2.515±0.00 2.143±0.00 1.861±0.00 1.785±0.00 2.137±0.10 0.286±0.00 2.747±0.60 1.428±0.68 2.369±0.17 0.090±0.00 1.877±0.60 1.348±0.19 7.767±1.35
ENST00000537413 1.104±0.00 N/A 0.928±0.00 N/A 1.224±0.00 1.024±0.00 0.243±0.00 0.648±0.00 1.189±0.00 1.811±0.00 0.604±0.12 2.468±0.44 1.146±0.57 6.544±0.38
ENST00000554874 1.784±0.00 5.563±0.00 N/A N/A N/A 2.548±0.00 0.631±0.00 5.263±0.00 6.156±0.00 6.674±0.00 N/A 4.968±0.33 2.156±1.01 N/A
ENST00000555652 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 6.855±0.00 N/A N/A N/A
ENST00000555818 N/A 1.036±0.00 0.585±0.00 7.880±3.39 0.860±0.00 N/A 0.300±0.00 N/A 0.958±0.00 1.042±0.00 0.562±0.00 1.267±0.80 0.505±0.00 3.137±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002M7 CIL_0002M7_0001 CGP 14:70907405-71741229

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003674 ND molecular_function
GO:0005096 IEA GTPase activator activity
GO:0005515 IEA protein binding
GO:0005575 ND cellular_component
GO:0005737 IEA cytoplasm
GO:0008150 ND biological_process
GO:0014069 ISS postsynaptic density
GO:0030054 IEA cell junction
GO:0031532 ISS actin cytoskeleton reorganization
GO:0032317 ISS regulation of Rap GTPase activity
GO:0032861 ISS activation of Rap GTPase activity
GO:0043197 ISS dendritic spine
GO:0043547 IEA positive regulation of GTPase activity
GO:0045211 IEA postsynaptic membrane
GO:0046875 IEA ephrin receptor binding
GO:0048013 ISS ephrin receptor signaling pathway
GO:0048167 ISS regulation of synaptic plasticity
GO:0050770 ISS regulation of axonogenesis
GO:0051056 IEA regulation of small GTPase mediated signal transduction
GO:0061001 ISS regulation of dendritic spine morphogenesis

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000020134 sipa1l1 signal-induced proliferation-associated 1 like 1 protein_coding Danio_rerio
ENSMUSG00000042700 Sipa1l1 signal-induced proliferation-associated 1 like 1 protein_coding Mus_musculus

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