C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: dipeptidyl-peptidase 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000197635 DPP4 9606 - 2:161992241-162074542 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000360534 DPP4-001 161992241-162074542 protein_coding
  ENST00000413651 DPP4-007 162038988-162074002 nonsense_mediated_decay
  ENST00000416189 DPP4-004 162038342-162047498 nonsense_mediated_decay
  ENST00000434918 DPP4-002 161993283-162074122 nonsense_mediated_decay
  ENST00000461836 DPP4-005 162038374-162073463 retained_intron
  ENST00000468903 DPP4-008 162016820-162021593 processed_transcript
  ENST00000490286 DPP4-006 161995178-162073486 retained_intron
  ENST00000491591 DPP4-010 161994961-162017551 processed_transcript
  ENST00000494507 DPP4-011 162005645-162014462 retained_intron
  ENST00000497461 DPP4-003 162038342-162073596 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000360534ENST00000490286ENST00000491591ENST00000494507
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000360534 5.940±0.00 1.056±0.00 2.702±0.00 0.109±0.00 1.798±1.20 0.740±0.00 0.392±0.00 5.100±2.91 1.972±0.00 2.269±0.28 1.149±0.00 4.223±0.81 27.691±17.41 0.289±0.00
ENST00000490286 N/A N/A 3.205±0.00 0.196±0.08 N/A N/A N/A N/A 1.478±0.00 2.479±0.00 0.338±0.00 5.451±0.00 N/A 0.294±0.00
ENST00000491591 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.389±0.00
ENST00000494507 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 26.156±0.00 134.782±0.00 0.908±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005KV CIL_0005KV_0001 CGP 2:161424332-162074542
CIL_00039X CIL_00039X_0001 CGP 2:161992241-162152404

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001666 IDA response to hypoxia
GO:0002020 IPI protease binding
GO:0004252 IEA serine-type endopeptidase activity
GO:0005102 IPI receptor binding
GO:0005515 IPI protein binding
GO:0005765 IDA lysosomal membrane
GO:0005886 IDA plasma membrane
GO:0005925 IDA focal adhesion
GO:0006508 IEA proteolysis
GO:0007155 IEA cell adhesion
GO:0008236 IDA:IEA serine-type peptidase activity
GO:0008239 IDA dipeptidyl-peptidase activity
GO:0008284 IDA positive regulation of cell proliferation
GO:0009986 IDA cell surface
GO:0010716 IDA negative regulation of extracellular matrix disassembly
GO:0016020 IDA:IEA membrane
GO:0016021 IEA integral component of membrane
GO:0016324 IDA apical plasma membrane
GO:0030027 IDA lamellipodium
GO:0030139 IDA endocytic vesicle
GO:0031295 IDA T cell costimulation
GO:0033632 IDA regulation of cell-cell adhesion mediated by integrin
GO:0042110 IDA T cell activation
GO:0042802 IPI identical protein binding
GO:0042803 IPI protein homodimerization activity
GO:0043542 IDA endothelial cell migration
GO:0046581 IEA intercellular canaliculus
GO:0070062 IDA extracellular vesicular exosome
GO:0071438 IDA invadopodium membrane

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000088928 DPP4 dipeptidyl-peptidase 4 protein_coding Danio_rerio
ENSMUSG00000035000 Dpp4 dipeptidylpeptidase 4 protein_coding Mus_musculus

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