C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: dipeptidylpeptidase 4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000035000 Dpp4 10090 - 2:62330073-62412231 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000047812 Dpp4-001 62330073-62412231 protein_coding
  ENSMUST00000129738 Dpp4-005 62352255-62357707 processed_transcript
  ENSMUST00000149306 Dpp4-002 62374255-62412021 retained_intron
  ENSMUST00000150979 Dpp4-004 62364717-62378248 retained_intron
  ENSMUST00000151818 Dpp4-003 62407702-62411859 processed_transcript
  ENSMUST00000156871 Dpp4-006 62334473-62345146 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000047812
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000047812 6.829±2.64 0.512±0.06 1.721±0.56 0.362±0.19 9.769±1.66 5.226±0.70 1.261±0.23 14.825±1.07 12.526±11.31 20.065±1.54 0.427±0.09 2.200±0.84 1.664±1.13 0.259±0.23

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005KV CIL_0005KV_0002 CGP 2:62046462-62412231
CIL_00039X CIL_00039X_0002 CGP 2:62330073-62483650

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001666 IEA response to hypoxia
GO:0002020 ISS protease binding
GO:0004252 IEA serine-type endopeptidase activity
GO:0005102 ISS receptor binding
GO:0005515 IEA protein binding
GO:0005765 IEA lysosomal membrane
GO:0005886 IEA plasma membrane
GO:0005925 IEA focal adhesion
GO:0006508 IEA proteolysis
GO:0007155 IEA cell adhesion
GO:0008239 ISS dipeptidyl-peptidase activity
GO:0008284 ISS positive regulation of cell proliferation
GO:0009986 ISS cell surface
GO:0010716 ISS negative regulation of extracellular matrix disassembly
GO:0016021 IEA integral component of membrane
GO:0016324 IEA apical plasma membrane
GO:0030027 ISS lamellipodium
GO:0030139 ISS endocytic vesicle
GO:0031295 ISS T cell costimulation
GO:0033632 IEA regulation of cell-cell adhesion mediated by integrin
GO:0042110 IEA T cell activation
GO:0042802 IEA identical protein binding
GO:0042803 ISS protein homodimerization activity
GO:0043542 ISS endothelial cell migration
GO:0046581 IDA intercellular canaliculus
GO:0070062 IEA extracellular vesicular exosome
GO:0071438 ISS invadopodium membrane

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000088928 DPP4 dipeptidyl-peptidase 4 protein_coding Danio_rerio
ENSG00000197635 DPP4 dipeptidyl-peptidase 4 protein_coding Homo_sapiens

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