C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: histone cluster 4, H4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000197837 HIST4H4 9606 - 12:14767999-14771131 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000358064 HIST4H4-001 14767999-14771131 nonsense_mediated_decay
  ENST00000537096 HIST4H4-006 14768158-14769622 processed_transcript
  ENST00000537853 HIST4H4-004 14768939-14770276 processed_transcript
  ENST00000539745 HIST4H4-002 14770555-14771131 protein_coding
  ENST00000540565 HIST4H4-005 14768996-14770793 processed_transcript
  ENST00000541592 HIST4H4-003 14768925-14770170 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000358064ENST00000537096ENST00000537853ENST00000539745ENST00000540565ENST00000541592
Transcript ID Adipose Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000358064 N/A N/A 0.092±0.00 N/A 0.028±0.00 0.169±0.00 0.272±0.00 0.014±0.00 N/A N/A 0.434±0.00 0.142±0.00 0.089±0.00
ENST00000537096 N/A N/A N/A 0.372±0.00 N/A 0.882±0.00 N/A N/A N/A 0.519±0.00 N/A N/A 1.620±0.00
ENST00000537853 N/A N/A 1.703±0.00 N/A N/A 0.640±0.00 0.732±0.00 0.307±0.00 N/A 0.527±0.00 N/A 0.172±0.00 N/A
ENST00000539745 0.532±0.00 3.082±0.00 2.943±2.18 3.499±0.00 6.182±5.83 0.657±0.11 3.532±0.00 4.581±4.33 6.466±0.00 1.234±0.00 11.526±0.00 N/A 0.479±0.00
ENST00000540565 N/A N/A N/A 0.170±0.00 N/A 0.233±0.03 N/A N/A 0.804±0.00 N/A N/A 0.109±0.00 N/A
ENST00000541592 0.291±0.00 N/A 0.328±0.00 0.271±0.00 0.172±0.00 N/A N/A 0.132±0.00 0.328±0.00 N/A 1.337±0.00 N/A 0.351±0.08

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000228 IDA nuclear chromosome
GO:0000278 TAS mitotic cell cycle
GO:0000723 TAS telomere maintenance
GO:0000786 TAS:IEA nucleosome
GO:0003677 TAS:IEA DNA binding
GO:0005515 IPI protein binding
GO:0005576 TAS extracellular region
GO:0005634 IDA:IEA nucleus
GO:0005654 TAS nucleoplasm
GO:0006325 TAS chromatin organization
GO:0006334 TAS nucleosome assembly
GO:0006335 IDA DNA replication-dependent nucleosome assembly
GO:0006336 IDA DNA replication-independent nucleosome assembly
GO:0006352 IEA DNA-templated transcription, initiation
GO:0016020 IDA membrane
GO:0034080 TAS CENP-A containing nucleosome assembly
GO:0035574 TAS histone H4-K20 demethylation
GO:0035575 TAS histone demethylase activity (H4-K20 specific)
GO:0043234 IDA protein complex
GO:0044822 IDA poly(A) RNA binding
GO:0045653 IDA negative regulation of megakaryocyte differentiation
GO:0046982 IEA protein heterodimerization activity
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000074631 HIST1H4E histone cluster 4, H4 protein_coding Danio_rerio
ENSDARG00000091313 histone cluster 4, H4 protein_coding Danio_rerio

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