C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: aldo-keto reductase family 1, member B10 (aldose reductase)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000198074 AKR1B10 9606 + 7:134527592-134541408 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000359579 AKR1B10-001 134527592-134541408 protein_coding
  ENST00000475559 AKR1B10-005 134527620-134537087 processed_transcript
  ENST00000496435 AKR1B10-002 134537613-134541408 processed_transcript
  ENST00000498818 AKR1B10-004 134537580-134541408 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000359579ENST00000475559ENST00000496435
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000359579 0.070±0.00 N/A 0.020±0.00 0.143±0.00 8.070±7.32 N/A 2.098±0.00 1.539±0.29 0.123±0.00 0.429±0.00 1.540±1.29 0.089±0.01 0.154±0.00
ENST00000475559 N/A 0.271±0.00 0.020±0.00 0.115±0.00 N/A 0.141±0.00 0.489±0.00 N/A 0.181±0.00 N/A 3.289±3.00 0.052±0.00 0.191±0.00
ENST00000496435 N/A N/A N/A 0.149±0.09 0.175±0.00 0.035±0.00 1.741±0.04 0.770±0.26 N/A 3.077±0.00 0.840±0.32 N/A 0.150±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002GX CIL_0002GX_0001 CGP 7:134442350-134541408
CIL_0002GY CIL_0002GY_0001 CGP 7:134527592-134579875

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001523 TAS retinoid metabolic process
GO:0001758 IDA retinal dehydrogenase activity
GO:0004033 TAS aldo-keto reductase (NADP) activity
GO:0005515 IPI protein binding
GO:0005764 IEA lysosome
GO:0005829 TAS cytosol
GO:0006081 TAS cellular aldehyde metabolic process
GO:0007586 TAS digestion
GO:0007603 TAS phototransduction, visible light
GO:0008202 TAS steroid metabolic process
GO:0016488 IDA farnesol catabolic process
GO:0044597 IMP daunorubicin metabolic process
GO:0044598 IMP doxorubicin metabolic process
GO:0045550 IDA geranylgeranyl reductase activity
GO:0047718 IDA indanol dehydrogenase activity
GO:0055114 IEA oxidation-reduction process
GO:0070062 IDA extracellular vesicular exosome

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000045598 si:dkey-180p18.9 aldo-keto reductase family 1, member B1 (aldose reductase) protein_coding Danio_rerio
ENSMUSG00000029762 Akr1b8 aldo-keto reductase family 1, member B8 protein_coding Mus_musculus
ENSMUSG00000052131 Akr1b7 aldo-keto reductase family 1, member B7 protein_coding Mus_musculus
ENSMUSG00000061758 Akr1b10 aldo-keto reductase family 1, member B10 (aldose reductase) protein_coding Mus_musculus

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