C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: thioredoxin reductase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000198431 TXNRD1 9606 + 12:104215779-104350305 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000354940 TXNRD1-201 104286682-104350305 protein_coding
  ENST00000388854 TXNRD1-202 104286682-104350305 protein_coding
  ENST00000397736 TXNRD1-203 104286682-104350305 protein_coding
  ENST00000429002 TXNRD1-204 104215779-104350305 protein_coding
  ENST00000503506 TXNRD1-003 104286682-104350277 protein_coding
  ENST00000524698 TXNRD1-006 104287368-104348644 protein_coding
  ENST00000525265 TXNRD1-019 104334127-104348583 retained_intron
  ENST00000525566 TXNRD1-001 104215779-104350283 protein_coding
  ENST00000526006 TXNRD1-010 104251546-104284406 processed_transcript
  ENST00000526207 TXNRD1-018 104287032-104289403 retained_intron
  ENST00000526266 TXNRD1-012 104286002-104315826 protein_coding
  ENST00000526390 TXNRD1-017 104286990-104350274 protein_coding
  ENST00000526580 TXNRD1-005 104287057-104318943 protein_coding
  ENST00000526691 TXNRD1-002 104286881-104350283 protein_coding
  ENST00000526950 TXNRD1-009 104309851-104348483 protein_coding
  ENST00000527335 TXNRD1-014 104288895-104319573 protein_coding
  ENST00000527688 TXNRD1-007 104288718-104350283 nonsense_mediated_decay
  ENST00000528079 TXNRD1-020 104287049-104311406 protein_coding
  ENST00000529546 TXNRD1-004 104287022-104348828 protein_coding
  ENST00000529751 TXNRD1-021 104287024-104327574 protein_coding
  ENST00000529784 TXNRD1-015 104287322-104313316 protein_coding
  ENST00000531689 TXNRD1-013 104286995-104315832 protein_coding
  ENST00000531691 TXNRD1-016 104286925-104315901 protein_coding
  ENST00000534282 TXNRD1-011 104224816-104258268 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000354940ENST00000503506ENST00000524698ENST00000525265ENST00000525566ENST00000526390ENST00000526691ENST00000526950ENST00000527688ENST00000529546
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000354940 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 4.895±0.00
ENST00000503506 N/A N/A N/A 4.415±0.00 6.506±0.00 9.755±0.00 4.786±0.00 N/A 23.947±0.00 5.247±0.00 N/A 12.467±5.09 N/A N/A
ENST00000524698 N/A N/A 2.120±0.00 4.472±0.00 N/A N/A N/A N/A N/A N/A N/A 14.768±0.00 N/A 8.205±0.00
ENST00000525265 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 29.662±0.00 N/A
ENST00000525566 N/A N/A 1.380±0.00 5.062±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A 4.262±0.00
ENST00000526390 4.499±0.00 4.733±0.00 N/A 2.821±0.00 N/A N/A N/A N/A 2.224±0.00 N/A N/A N/A 3.163±0.00 N/A
ENST00000526691 N/A N/A N/A 2.552±0.00 1.596±0.00 6.516±3.07 3.131±1.68 14.386±0.00 17.039±0.00 10.426±5.98 3.693±0.00 9.083±3.77 5.894±1.69 7.136±0.00
ENST00000526950 N/A N/A N/A N/A 8.600±0.00 N/A N/A 3.267±0.00 N/A 6.864±0.00 N/A N/A N/A N/A
ENST00000527688 N/A 3.435±0.00 N/A N/A 1.683±0.00 N/A N/A N/A N/A 3.030±0.00 N/A 6.520±0.00 N/A N/A
ENST00000529546 N/A N/A N/A N/A N/A N/A 7.086±0.00 N/A N/A N/A N/A 13.402±0.00 7.658±0.00 5.913±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0004AC CIL_0004AC_0001 CGP 12:104117077-104350305

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001707 IEA mesoderm formation
GO:0004791 IEA thioredoxin-disulfide reductase activity
GO:0005634 IDA nucleus
GO:0005730 IDA nucleolus
GO:0005737 IEA cytoplasm
GO:0005739 IEA mitochondrion
GO:0005829 IEA cytosol
GO:0007369 IEA gastrulation
GO:0008033 IEA tRNA processing
GO:0008283 IEA cell proliferation
GO:0009055 IEA electron carrier activity
GO:0015035 IEA protein disulfide oxidoreductase activity
GO:0016491 IEA oxidoreductase activity
GO:0016668 IEA oxidoreductase activity, acting on a sulfur group of donors, NAD(P) as acceptor
GO:0045454 IEA cell redox homeostasis
GO:0050660 IEA flavin adenine dinucleotide binding
GO:0050661 IEA NADP binding
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000017864 txnrd1 thioredoxin reductase 1 protein_coding Danio_rerio
ENSMUSG00000020250 Txnrd1 thioredoxin reductase 1 protein_coding Mus_musculus

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