C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: aldo-keto reductase family 1, member C4
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000198610 AKR1C4 9606 + 10:5195462-5218949 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000263126 AKR1C4-201 5196835-5218947 protein_coding
  ENST00000380448 AKR1C4-001 5195463-5218949 protein_coding
  ENST00000469875 AKR1C4-002 5195462-5196922 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastHeartKidneyLiverOvaryPlacentaTestisENST00000263126ENST00000380448
Transcript ID Adipose Adrenal Brain Breast Heart Kidney Liver Ovary Placenta Testis
ENST00000263126 0.011±0.00 0.023±0.00 0.028±0.00 0.132±0.03 0.021±0.00 30.877±30.69 75.313±0.00 0.187±0.07 0.048±0.00 0.352±0.03
ENST00000380448 N/A N/A N/A N/A N/A N/A N/A 0.036±0.00 N/A 0.063±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002HN CIL_0002HN_0003 CGP 10:5035354-5218949

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001523 TAS retinoid metabolic process
GO:0001758 IDA retinal dehydrogenase activity
GO:0004033 TAS aldo-keto reductase (NADP) activity
GO:0005737 TAS cytoplasm
GO:0005829 TAS cytosol
GO:0006699 TAS bile acid biosynthetic process
GO:0007603 TAS phototransduction, visible light
GO:0008202 TAS steroid metabolic process
GO:0008206 TAS bile acid metabolic process
GO:0008209 TAS androgen metabolic process
GO:0009055 TAS electron carrier activity
GO:0015125 TAS bile acid transmembrane transporter activity
GO:0015721 TAS bile acid and bile salt transport
GO:0016655 IDA oxidoreductase activity, acting on NAD(P)H, quinone or similar compound as acceptor
GO:0044281 TAS small molecule metabolic process
GO:0044597 IMP daunorubicin metabolic process
GO:0044598 IMP doxorubicin metabolic process
GO:0047023 IDA androsterone dehydrogenase activity
GO:0047743 IEA chlordecone reductase activity
GO:0055114 IEA oxidation-reduction process
GO:0070062 IDA extracellular vesicular exosome
GO:0071395 IDA cellular response to jasmonic acid stimulus

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000021207 Akr1c21 aldo-keto reductase family 1, member C21 protein_coding Mus_musculus
ENSMUSG00000021210 Akr1c6 aldo-keto reductase family 1, member C6 protein_coding Mus_musculus
ENSMUSG00000021214 Akr1c18 aldo-keto reductase family 1, member C18 protein_coding Mus_musculus
ENSMUSG00000025955 Akr1cl aldo-keto reductase family 1, member C-like protein_coding Mus_musculus
ENSMUSG00000033715 Akr1c14 aldo-keto reductase family 1, member C14 protein_coding Mus_musculus
ENSMUSG00000054757 Akr1c20 aldo-keto reductase family 1, member C20 protein_coding Mus_musculus

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