C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: aldo-keto reductase family 1, member C6
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000021210 Akr1c6 10090 + 13:4434306-4457530 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000021630 Akr1c6-001 4434306-4457530 protein_coding
  ENSMUST00000128695 Akr1c6-002 4434432-4435046 processed_transcript
  ENSMUST00000156277 Akr1c6-003 4436146-4449315 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBreastHeartKidneyLiverLungMuscleOvaryPlacentaENSMUST00000021630ENSMUST00000156277
Transcript ID Adipose Adrenal Breast Heart Kidney Liver Lung Muscle Ovary Placenta
ENSMUST00000021630 N/A N/A 0.274±0.03 0.039±0.01 0.079±0.04 139.027±130.54 0.068±0.02 0.029±0.01 0.448±0.19 0.012±0.00
ENSMUST00000156277 0.129±0.03 0.240±0.00 0.389±0.24 N/A 0.208±0.00 N/A N/A N/A 0.706±0.33 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0002HN CIL_0002HN_0004 CGP 13:4434306-4523344

Gene Ontology

GO IDEvidence TypeGO Description
GO:0004033 IDA aldo-keto reductase (NADP) activity
GO:0004303 IDA estradiol 17-beta-dehydrogenase activity
GO:0006694 IDA steroid biosynthetic process
GO:0008202 IDA steroid metabolic process
GO:0048025 IMP negative regulation of mRNA splicing, via spliceosome
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSG00000151632 AKR1C2 aldo-keto reductase family 1, member C2 protein_coding Homo_sapiens
ENSG00000187134 AKR1C1 aldo-keto reductase family 1, member C1 protein_coding Homo_sapiens
ENSG00000196139 AKR1C3 aldo-keto reductase family 1, member C3 protein_coding Homo_sapiens
ENSG00000198610 AKR1C4 aldo-keto reductase family 1, member C4 protein_coding Homo_sapiens

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