C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: delta-like 1 (Drosophila)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000198719 DLL1 9606 - 6:170282206-170290473 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000366756 DLL1-001 170282206-170290473 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000366756
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000366756 13.368±0.00 2.139±0.00 0.189±0.00 2.227±1.66 1.567±0.70 5.036±0.00 0.872±0.00 2.268±0.00 0.683±0.56 2.784±2.11 0.549±0.00 9.006±10.17 1.828±0.66 1.595±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008DG CIL_0008DG_0001 VISTA 6:170138007-170739776
CIL_0002HB CIL_0002HB_0002 CGP 6:170282206-170407065

Gene Ontology

GO IDEvidence TypeGO Description
GO:0001709 NAS cell fate determination
GO:0001756 IEA somitogenesis
GO:0001757 IEA somite specification
GO:0001947 ISS heart looping
GO:0005112 IPI Notch binding
GO:0005509 IEA calcium ion binding
GO:0005515 IPI:IEA protein binding
GO:0005576 NAS extracellular region
GO:0005886 TAS plasma membrane
GO:0005887 NAS integral component of plasma membrane
GO:0007154 IEA cell communication
GO:0007219 NAS:IEA Notch signaling pathway
GO:0007220 TAS Notch receptor processing
GO:0007267 IEA cell-cell signaling
GO:0007275 IEA multicellular organismal development
GO:0007368 ISS determination of left/right symmetry
GO:0007386 IEA compartment pattern specification
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0030097 NAS hemopoiesis
GO:0030154 TAS cell differentiation
GO:0030155 TAS regulation of cell adhesion
GO:0031410 IEA cytoplasmic vesicle
GO:0032693 IMP negative regulation of interleukin-10 production
GO:0045596 IEA negative regulation of cell differentiation
GO:0045608 IEA negative regulation of auditory receptor cell differentiation
GO:0045638 IEA negative regulation of myeloid cell differentiation
GO:0045665 IEA negative regulation of neuron differentiation
GO:0045747 IEA positive regulation of Notch signaling pathway
GO:0045944 ISS positive regulation of transcription from RNA polymerase II promoter
GO:0048839 IEA inner ear development
GO:0050767 IEA regulation of neurogenesis
GO:0070986 IEA left/right axis specification
GO:0072014 IEA proximal tubule development
GO:0072070 IEA loop of Henle development
GO:0097150 IEP neuronal stem cell maintenance

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000010791 dla deltaA protein_coding Danio_rerio
ENSDARG00000020219 dld deltaD protein_coding Danio_rerio
ENSMUSG00000014773 Dll1 delta-like 1 (Drosophila) protein_coding Mus_musculus

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