C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: delta-like 1 (Drosophila)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000014773 Dll1 10090 - 17:15367354-15376872 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000014917 Dll1-001 15367354-15375976 protein_coding
  ENSMUST00000124196 Dll1-003 15371624-15375100 retained_intron
  ENSMUST00000129395 Dll1-004 15370609-15374072 processed_transcript
  ENSMUST00000140784 Dll1-006 15367525-15368390 retained_intron
  ENSMUST00000143460 Dll1-002 15374794-15376872 processed_transcript
  ENSMUST00000152416 Dll1-005 15370256-15371831 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaENSMUST00000014917ENSMUST00000124196ENSMUST00000129395ENSMUST00000140784
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta
ENSMUST00000014917 1.124±0.31 N/A 2.620±0.05 11.199±3.05 0.922±0.43 1.884±0.17 0.418±0.14 0.714±0.26 0.349±0.09 1.514±0.43 0.930±0.30 1.180±0.13 1.442±1.33
ENSMUST00000124196 N/A 1.212±0.28 N/A N/A 2.765±1.26 N/A 1.631±0.06 2.597±0.00 N/A N/A N/A 2.311±0.00 N/A
ENSMUST00000129395 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.939±0.00
ENSMUST00000140784 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.257±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008DG CIL_0008DG_0002 VISTA 17:15140120-15741360
CIL_0002HB CIL_0002HB_0003 CGP 17:15367354-15433580

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001701 NAS in utero embryonic development
GO:0001756 IGI somitogenesis
GO:0001757 IMP somite specification
GO:0001947 IMP heart looping
GO:0005112 IPI Notch binding
GO:0005509 IEA calcium ion binding
GO:0005515 IPI protein binding
GO:0005886 IDA plasma membrane
GO:0007219 TAS Notch signaling pathway
GO:0007267 IDA cell-cell signaling
GO:0007368 IMP determination of left/right symmetry
GO:0007386 IMP compartment pattern specification
GO:0007399 NAS nervous system development
GO:0009887 NAS organ morphogenesis
GO:0009912 NAS auditory receptor cell fate commitment
GO:0016021 IEA integral component of membrane
GO:0031410 IDA cytoplasmic vesicle
GO:0032693 IEA negative regulation of interleukin-10 production
GO:0042472 NAS inner ear morphogenesis
GO:0042475 NAS odontogenesis of dentin-containing tooth
GO:0042491 NAS auditory receptor cell differentiation
GO:0045596 IMP negative regulation of cell differentiation
GO:0045608 IMP negative regulation of auditory receptor cell differentiation
GO:0045638 IDA negative regulation of myeloid cell differentiation
GO:0045665 IMP negative regulation of neuron differentiation
GO:0045747 IDA positive regulation of Notch signaling pathway
GO:0045944 IMP positive regulation of transcription from RNA polymerase II promoter
GO:0048839 IMP inner ear development
GO:0050767 IMP regulation of neurogenesis
GO:0061314 IC Notch signaling involved in heart development
GO:0070986 IMP left/right axis specification
GO:0072014 IEP proximal tubule development
GO:0072070 IEP loop of Henle development
GO:0097150 IEA neuronal stem cell maintenance

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000010791 dla deltaA protein_coding Danio_rerio
ENSDARG00000020219 dld deltaD protein_coding Danio_rerio
ENSG00000198719 DLL1 delta-like 1 (Drosophila) protein_coding Homo_sapiens

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