C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000203857 HSD3B1 9606 + 1:119507198-119515054 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000369413 HSD3B1-001 119507203-119515054 protein_coding
  ENST00000487520 HSD3B1-003 119507240-119508024 retained_intron
  ENST00000492140 HSD3B1-002 119507213-119511952 retained_intron
  ENST00000528909 HSD3B1-004 119507318-119514800 protein_coding
  ENST00000531340 HSD3B1-005 119507198-119511602 protein_coding

Homo sapiens EnsemblGRCh38

Genome
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Genes
Gene structures from Ensembl
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Transcripts
Structures from Ensembl
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Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverOvaryPlacentaTestisENST00000369413ENST00000487520ENST00000492140ENST00000528909ENST00000531340
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Ovary Placenta Testis
ENST00000369413 N/A N/A N/A N/A N/A N/A N/A N/A N/A 2.503±3.43 108.538±79.28 N/A
ENST00000487520 N/A N/A 0.255±0.00 0.123±0.08 N/A N/A 0.073±0.00 0.070±0.00 0.245±0.00 0.453±0.39 N/A N/A
ENST00000492140 N/A 0.065±0.00 N/A 0.111±0.00 0.037±0.00 N/A N/A 0.186±0.00 N/A 0.112±0.00 N/A 0.071±0.01
ENST00000528909 N/A N/A N/A 0.035±0.01 N/A N/A N/A N/A 0.031±0.00 N/A N/A N/A
ENST00000531340 0.098±0.00 N/A N/A N/A 0.020±0.00 0.050±0.00 N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0005IA CIL_0005IA_0001 CGP 1:119414931-119515054

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003824 IEA catalytic activity
GO:0003854 IEA:ISS 3-beta-hydroxy-delta5-steroid dehydrogenase activity
GO:0004769 ISS steroid delta-isomerase activity
GO:0005743 IDA mitochondrial inner membrane
GO:0005758 IDA mitochondrial intermembrane space
GO:0005789 TAS endoplasmic reticulum membrane
GO:0006694 IEA:ISS steroid biosynthetic process
GO:0006702 TAS androgen biosynthetic process
GO:0006703 TAS estrogen biosynthetic process
GO:0006704 TAS glucocorticoid biosynthetic process
GO:0006705 TAS mineralocorticoid biosynthetic process
GO:0008152 IEA metabolic process
GO:0008202 TAS steroid metabolic process
GO:0009058 IEA biosynthetic process
GO:0016021 IEA integral component of membrane
GO:0016491 IEA oxidoreductase activity
GO:0016616 IEA oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0030868 ISS smooth endoplasmic reticulum membrane
GO:0044281 TAS small molecule metabolic process
GO:0050662 IEA coenzyme binding
GO:0055114 IEA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000019747 hsd3b2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 protein_coding Danio_rerio
ENSDARG00000069926 hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 protein_coding Danio_rerio
ENSMUSG00000027869 Hsd3b6 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 6 protein_coding Mus_musculus
ENSMUSG00000027871 Hsd3b1 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 protein_coding Mus_musculus
ENSMUSG00000038092 Hsd3b5 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 5 protein_coding Mus_musculus
ENSMUSG00000062410 Hsd3b3 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 3 protein_coding Mus_musculus
ENSMUSG00000063730 Hsd3b2 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 2 protein_coding Mus_musculus
ENSMUSG00000090817 Gm4450 predicted gene 4450 protein_coding Mus_musculus
ENSMUSG00000095143 Hsd3b4 hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 4 protein_coding Mus_musculus
ENSMUSG00000095388 Gm10681 predicted gene 10681 protein_coding Mus_musculus

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