C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000204267 TAP2 9606 - 6:32821833-32838780 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000374897 TAP2-001 32825415-32838780 protein_coding
  ENST00000374899 TAP2-002 32821833-32838727 protein_coding
  ENST00000464100 TAP2-004 32828944-32830727 retained_intron
  ENST00000485701 TAP2-003 32832295-32832733 processed_transcript
  ENST00000620123 TAP2-201 32825410-32838770 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000374897ENST00000374899ENST00000464100ENST00000485701ENST00000620123
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000374897 7.503±0.00 11.560±0.00 0.354±0.00 2.256±1.58 3.682±0.00 2.863±0.00 1.723±1.31 2.764±0.00 0.847±0.54 16.026±0.00 1.182±0.94 6.760±0.00 3.093±1.38 2.045±0.00
ENST00000374899 N/A N/A N/A 0.557±0.00 N/A N/A N/A 1.641±0.00 N/A N/A N/A 2.625±0.43 5.586±1.29 N/A
ENST00000464100 N/A N/A N/A N/A N/A N/A N/A 7.512±0.00 3.817±0.00 N/A 0.760±0.00 11.238±0.00 8.015±0.00 1.986±0.00
ENST00000485701 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 26.245±0.00 N/A N/A
ENST00000620123 N/A N/A 0.358±0.00 0.713±0.00 N/A N/A 0.525±0.00 0.863±0.00 0.296±0.00 6.658±0.00 0.255±0.00 3.076±0.72 2.250±0.57 0.637±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0002474 TAS antigen processing and presentation of peptide antigen via MHC class I
GO:0002479 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0002481 IBA antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent
GO:0002485 IBA antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent
GO:0002489 IMP antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent
GO:0002591 IBA positive regulation of antigen processing and presentation of peptide antigen via MHC class I
GO:0005215 IDA transporter activity
GO:0005515 IPI protein binding
GO:0005524 IDA:IEA ATP binding
GO:0005789 TAS endoplasmic reticulum membrane
GO:0006200 IEA ATP catabolic process
GO:0006810 IEA transport
GO:0015197 IGI peptide transporter activity
GO:0015433 IMP peptide antigen-transporting ATPase activity
GO:0015440 IEA peptide-transporting ATPase activity
GO:0016020 IDA membrane
GO:0016021 IDA:IEA integral component of membrane
GO:0016887 IEA ATPase activity
GO:0019060 IMP intracellular transport of viral protein in host cell
GO:0019885 IMP:IEA antigen processing and presentation of endogenous peptide antigen via MHC class I
GO:0023029 IPI MHC class Ib protein binding
GO:0030176 IDA:IEA integral component of endoplasmic reticulum membrane
GO:0042287 IEA MHC protein binding
GO:0042590 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0042626 IEA ATPase activity, coupled to transmembrane movement of substances
GO:0042825 IDA:IEA TAP complex
GO:0046967 IMP cytosol to ER transport
GO:0046968 IMP peptide antigen transport
GO:0046978 IPI TAP1 binding
GO:0046980 ISS tapasin binding
GO:0055085 IBA:IEA transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000033446 si:dkey-57h18.2 si:dkey-57h18.2 protein_coding Danio_rerio
ENSDARG00000036787 abcb3l1 ATP-binding cassette, sub-family B (MDR/TAP), member 3 like 1 protein_coding Danio_rerio
ENSMUSG00000024339 Tap2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) protein_coding Mus_musculus

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