C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: transporter 2, ATP-binding cassette, sub-family B (MDR/TAP)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000024339 Tap2 10090 + 17:34203527-34216321 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000025197 Tap2-001 34203527-34216321 protein_coding
  ENSMUST00000127543 Tap2-002 34204567-34216318 retained_intron
  ENSMUST00000131105 Tap2-004 34205100-34205567 protein_coding
  ENSMUST00000138491 Tap2-003 34204080-34205368 protein_coding
  ENSMUST00000145528 Tap2-005 34207706-34209220 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000025197ENSMUST00000127543
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000025197 5.002±0.89 7.791±2.13 4.697±0.00 0.271±0.19 12.260±0.53 4.296±0.69 1.876±0.34 2.264±0.09 1.319±0.44 6.900±1.19 0.829±0.21 4.390±0.40 1.232±0.21 0.203±0.11
ENSMUST00000127543 22.759±3.88 23.697±1.60 15.440±0.38 1.085±1.15 37.704±11.76 13.881±1.97 8.552±1.60 9.763±1.27 5.664±3.39 26.886±2.23 3.151±0.72 16.504±1.46 4.067±2.68 0.569±0.11

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001916 IDA positive regulation of T cell mediated cytotoxicity
GO:0002237 IMP response to molecule of bacterial origin
GO:0002481 IMP antigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent
GO:0002485 IDA antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-dependent
GO:0002489 IDA antigen processing and presentation of endogenous peptide antigen via MHC class Ib via ER pathway, TAP-dependent
GO:0002591 IBA positive regulation of antigen processing and presentation of peptide antigen via MHC class I
GO:0005515 IPI protein binding
GO:0005524 IEA ATP binding
GO:0005783 IEA endoplasmic reticulum
GO:0006200 IEA ATP catabolic process
GO:0015031 IEA protein transport
GO:0015197 IEA peptide transporter activity
GO:0015833 IEA peptide transport
GO:0016021 IBA integral component of membrane
GO:0042626 IBA ATPase activity, coupled to transmembrane movement of substances
GO:0046978 IPI TAP1 binding
GO:0046980 ISS tapasin binding
GO:0055085 IBA transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000033446 si:dkey-57h18.2 si:dkey-57h18.2 protein_coding Danio_rerio
ENSDARG00000036787 abcb3l1 ATP-binding cassette, sub-family B (MDR/TAP), member 3 like 1 protein_coding Danio_rerio
ENSG00000204267 TAP2 transporter 2, ATP-binding cassette, sub-family B (MDR/TAP) protein_coding Homo_sapiens
ENSG00000250264 TAP2 Uncharacterized protein {ECO:0000313|Ensembl:ENSP00000391806} protein_coding Homo_sapiens

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