C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ring finger protein 5, E3 ubiquitin protein ligase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000204308 RNF5 9606 + 6:32178354-32180793 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000375094 RNF5-001 32178354-32180793 protein_coding
  ENST00000487940 RNF5-002 32178437-32179773 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000375094
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000375094 27.769±0.00 33.216±0.00 6.070±0.00 22.581±6.72 12.776±6.63 21.371±15.08 21.966±16.28 38.096±23.28 25.484±19.89 41.082±0.00 17.451±5.12 27.078±15.16 38.292±16.38 24.225±12.85

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004842 IDA ubiquitin-protein transferase activity
GO:0005515 IPI:IEA protein binding
GO:0005739 IEA mitochondrion
GO:0005783 IEA endoplasmic reticulum
GO:0008270 IEA zinc ion binding
GO:0009617 IEA response to bacterium
GO:0010507 IEA negative regulation of autophagy
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0016567 IEA protein ubiquitination
GO:0016874 IEA ligase activity
GO:0031648 IEA protein destabilization
GO:0044257 IMP cellular protein catabolic process
GO:0046872 IEA metal ion binding
GO:0070534 IDA protein K63-linked ubiquitination
GO:0070936 IDA protein K48-linked ubiquitination
GO:0071712 IMP ER-associated misfolded protein catabolic process
GO:2000785 IEA regulation of autophagic vacuole assembly

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000075606 RNF5 ring finger protein 5, E3 ubiquitin protein ligase protein_coding Danio_rerio
ENSMUSG00000015478 Rnf5 ring finger protein 5 protein_coding Mus_musculus

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