C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000204628 GNB2L1 9606 - 5:181236909-181248096 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000376817 GNB2L1-035 181236937-181243903 protein_coding
  ENST00000502548 GNB2L1-003 181239038-181243904 retained_intron
  ENST00000502844 GNB2L1-017 181238124-181243370 protein_coding
  ENST00000502890 GNB2L1-028 181239070-181241880 retained_intron
  ENST00000502905 GNB2L1-032 181236929-181242206 protein_coding
  ENST00000503081 GNB2L1-018 181239150-181243906 protein_coding
  ENST00000503170 GNB2L1-014 181242250-181243904 processed_transcript
  ENST00000503494 GNB2L1-029 181239071-181243881 nonsense_mediated_decay
  ENST00000504128 GNB2L1-010 181236937-181241639 protein_coding
  ENST00000504325 GNB2L1-007 181236926-181243889 nonsense_mediated_decay
  ENST00000504726 GNB2L1-037 181236941-181243891 protein_coding
  ENST00000505461 GNB2L1-002 181240957-181243914 processed_transcript
  ENST00000506312 GNB2L1-016 181239134-181243902 nonsense_mediated_decay
  ENST00000507000 GNB2L1-011 181238170-181248096 protein_coding
  ENST00000507261 GNB2L1-020 181241437-181243902 retained_intron
  ENST00000507273 GNB2L1-023 181236937-181237860 retained_intron
  ENST00000507756 GNB2L1-024 181236929-181242246 protein_coding
  ENST00000508044 GNB2L1-027 181239287-181240473 retained_intron
  ENST00000508682 GNB2L1-022 181236937-181243902 nonsense_mediated_decay
  ENST00000508963 GNB2L1-019 181241443-181243903 retained_intron
  ENST00000509148 GNB2L1-025 181236929-181238195 protein_coding
  ENST00000509535 GNB2L1-031 181236937-181239584 protein_coding
  ENST00000510199 GNB2L1-012 181238120-181247576 protein_coding
  ENST00000511473 GNB2L1-006 181236909-181243916 nonsense_mediated_decay
  ENST00000511566 GNB2L1-034 181236934-181243880 protein_coding
  ENST00000511900 GNB2L1-036 181236945-181243880 protein_coding
  ENST00000512805 GNB2L1-001 181236937-181244209 protein_coding
  ENST00000512968 GNB2L1-021 181237020-181243893 protein_coding
  ENST00000513027 GNB2L1-015 181239539-181243904 protein_coding
  ENST00000513060 GNB2L1-008 181236961-181243947 retained_intron
  ENST00000514183 GNB2L1-009 181238206-181243742 retained_intron
  ENST00000514318 GNB2L1-013 181243042-181243908 processed_transcript
  ENST00000514455 GNB2L1-026 181236928-181238663 protein_coding
  ENST00000515417 GNB2L1-030 181239323-181243872 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000376817ENST00000502905ENST00000504325ENST00000508682ENST00000508963ENST00000509535ENST00000511473ENST00000511566ENST00000511900ENST00000512968
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000376817 N/A N/A 37.856±0.00 84.080±0.00 65.780±0.00 142.357±51.12 134.996±0.00 130.116±98.59 114.079±52.13 234.445±201.06 171.769±131.70 559.869±367.91 653.318±247.12 228.341±87.57
ENST00000502905 N/A N/A N/A N/A N/A N/A N/A 36.932±0.00 N/A N/A 46.088±0.00 N/A N/A N/A
ENST00000504325 295.594±0.00 365.220±0.00 29.853±0.00 56.717±24.34 253.697±0.00 87.648±39.32 38.089±0.00 40.301±0.00 39.535±0.00 55.469±0.00 55.290±0.00 728.043±130.67 327.796±65.73 204.119±0.00
ENST00000508682 N/A N/A N/A 32.585±0.00 63.764±0.00 55.821±0.00 31.988±0.00 46.701±0.00 73.905±0.00 26.950±0.00 64.456±0.00 85.120±0.00 N/A N/A
ENST00000508963 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 905.651±0.00 492.998±144.04 N/A
ENST00000509535 322.455±0.00 590.916±0.00 N/A N/A 365.444±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000511473 N/A N/A 26.479±0.00 27.502±0.00 49.430±0.00 N/A N/A 23.388±0.00 N/A 33.998±0.00 N/A 269.475±200.66 N/A N/A
ENST00000511566 244.976±0.00 326.968±0.00 N/A N/A 240.038±0.00 227.378±0.00 84.179±0.00 179.963±0.00 99.283±0.00 296.289±0.00 282.244±0.00 N/A N/A 214.710±0.00
ENST00000511900 N/A N/A N/A N/A N/A 179.330±0.00 91.057±0.00 194.687±0.00 153.928±0.00 359.225±0.00 350.618±0.00 N/A N/A N/A
ENST00000512968 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 439.865±0.00 696.906±0.00 260.995±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001649 IEA osteoblast differentiation
GO:0001891 IDA phagocytic cup
GO:0001934 IDA positive regulation of protein phosphorylation
GO:0005080 IDA protein kinase C binding
GO:0005102 NAS receptor binding
GO:0005515 IEA protein binding
GO:0005634 IDA nucleus
GO:0005737 IDA cytoplasm
GO:0005739 IMP mitochondrion
GO:0005829 IMP cytosol
GO:0005856 IEA cytoskeleton
GO:0006919 IMP activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007049 IEA cell cycle
GO:0007369 IEA gastrulation
GO:0008200 ISS ion channel inhibitor activity
GO:0008656 IMP cysteine-type endopeptidase activator activity involved in apoptotic process
GO:0010629 IMP negative regulation of gene expression
GO:0015935 ISS small ribosomal subunit
GO:0016020 IEA membrane
GO:0016032 IEA viral process
GO:0017148 ISS negative regulation of translation
GO:0019899 IPI enzyme binding
GO:0019903 IPI protein phosphatase binding
GO:0030178 ISS negative regulation of Wnt signaling pathway
GO:0030292 IDA protein tyrosine kinase inhibitor activity
GO:0030308 IDA negative regulation of cell growth
GO:0030335 IDA positive regulation of cell migration
GO:0030425 ISS dendrite
GO:0030496 IDA midbody
GO:0030822 IMP positive regulation of cAMP catabolic process
GO:0030971 IDA receptor tyrosine kinase binding
GO:0032436 IDA positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0032464 IMP positive regulation of protein homooligomerization
GO:0032880 ISS regulation of protein localization
GO:0032947 TAS protein complex scaffold
GO:0042169 IDA SH2 domain binding
GO:0042803 IDA protein homodimerization activity
GO:0043005 IEA neuron projection
GO:0043025 ISS neuronal cell body
GO:0043065 IMP positive regulation of apoptotic process
GO:0043547 IDA positive regulation of GTPase activity
GO:0044297 IEA cell body
GO:0044822 IDA poly(A) RNA binding
GO:0048471 IDA perinuclear region of cytoplasm
GO:0048511 IEA rhythmic process
GO:0050765 IMP negative regulation of phagocytosis
GO:0051302 ISS regulation of cell division
GO:0051343 IMP positive regulation of cyclic-nucleotide phosphodiesterase activity
GO:0051726 IDA regulation of cell cycle
GO:0051898 IMP negative regulation of protein kinase B signaling
GO:0051901 IMP positive regulation of mitochondrial depolarization
GO:0061099 IDA negative regulation of protein tyrosine kinase activity
GO:0070062 IDA extracellular vesicular exosome
GO:0090003 IEA regulation of establishment of protein localization to plasma membrane
GO:1903208 IGI negative regulation of hydrogen peroxide-induced neuron death
GO:2000114 ISS regulation of establishment of cell polarity
GO:2000543 ISS positive regulation of gastrulation
GO:2001244 IMP positive regulation of intrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000041619 gnb2l1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 protein_coding Danio_rerio
ENSMUSG00000020372 Gnb2l1 guanine nucleotide binding protein (G protein), beta polypeptide 2 like 1 protein_coding Mus_musculus

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