C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: guanine nucleotide binding protein (G protein), beta polypeptide 2 like 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000020372 Gnb2l1 10090 + 11:48800332-48806434 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000020640 Gnb2l1-001 48800360-48806434 protein_coding
  ENSMUST00000125166 Gnb2l1-004 48803152-48806073 processed_transcript
  ENSMUST00000136703 Gnb2l1-003 48800374-48802667 retained_intron
  ENSMUST00000136849 Gnb2l1-005 48805448-48806093 processed_transcript
  ENSMUST00000139959 Gnb2l1-002 48800357-48806088 processed_transcript
  ENSMUST00000142269 Gnb2l1-006 48800332-48804974 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000020640ENSMUST00000125166ENSMUST00000136703ENSMUST00000139959
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000020640 645.927±295.53 473.107±39.25 556.445±16.42 588.949±121.11 675.118±173.37 1033.306±51.37 234.237±83.12 466.801±59.51 681.496±397.68 525.651±32.14 94.286±48.23 1280.215±539.10 409.347±256.06 93.439±9.48
ENSMUST00000125166 N/A N/A N/A 251.210±0.00 437.532±80.41 N/A 163.950±11.88 218.093±0.00 213.289±0.00 N/A 121.337±27.72 850.605±457.00 1040.866±788.27 N/A
ENSMUST00000136703 481.165±162.22 429.036±107.48 N/A 229.693±67.27 698.638±106.36 492.736±89.98 N/A 209.710±17.44 N/A 298.357±35.11 109.351±15.65 1423.878±337.09 446.948±192.37 N/A
ENSMUST00000139959 N/A N/A 94.035±0.00 33.259±0.00 138.083±0.00 N/A N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0001649 IEA osteoblast differentiation
GO:0001891 ISS phagocytic cup
GO:0001934 ISS positive regulation of protein phosphorylation
GO:0004872 ISA receptor activity
GO:0005080 ISS protein kinase C binding
GO:0005515 IPI protein binding
GO:0005634 ISS nucleus
GO:0005737 IDA cytoplasm
GO:0005739 IEA mitochondrion
GO:0005829 IEA cytosol
GO:0005856 IEA cytoskeleton
GO:0006919 IEA activation of cysteine-type endopeptidase activity involved in apoptotic process
GO:0007049 IEA cell cycle
GO:0007369 IEA gastrulation
GO:0008104 ISA protein localization
GO:0008200 IDA ion channel inhibitor activity
GO:0008656 IEA cysteine-type endopeptidase activator activity involved in apoptotic process
GO:0010629 IEA negative regulation of gene expression
GO:0015935 IEA small ribosomal subunit
GO:0016020 IEA membrane
GO:0017148 IEA negative regulation of translation
GO:0019899 IEA enzyme binding
GO:0019903 IEA protein phosphatase binding
GO:0030178 ISS negative regulation of Wnt signaling pathway
GO:0030292 ISS protein tyrosine kinase inhibitor activity
GO:0030308 ISS negative regulation of cell growth
GO:0030335 ISS positive regulation of cell migration
GO:0030425 IDA dendrite
GO:0030496 ISS midbody
GO:0030822 IEA positive regulation of cAMP catabolic process
GO:0030971 ISS receptor tyrosine kinase binding
GO:0032436 ISS positive regulation of proteasomal ubiquitin-dependent protein catabolic process
GO:0032464 ISS positive regulation of protein homooligomerization
GO:0032880 ISS regulation of protein localization
GO:0035556 ISA intracellular signal transduction
GO:0042169 ISS SH2 domain binding
GO:0042803 IEA protein homodimerization activity
GO:0043005 IDA neuron projection
GO:0043025 IDA neuronal cell body
GO:0043065 ISS positive regulation of apoptotic process
GO:0043547 ISS positive regulation of GTPase activity
GO:0044297 IDA cell body
GO:0044822 IEA poly(A) RNA binding
GO:0048471 ISS perinuclear region of cytoplasm
GO:0048511 IEA rhythmic process
GO:0050765 ISS negative regulation of phagocytosis
GO:0051302 ISS regulation of cell division
GO:0051343 IEA positive regulation of cyclic-nucleotide phosphodiesterase activity
GO:0051726 ISS regulation of cell cycle
GO:0051898 IEA negative regulation of protein kinase B signaling
GO:0051901 IEA positive regulation of mitochondrial depolarization
GO:0061099 IEA negative regulation of protein tyrosine kinase activity
GO:0070062 IEA extracellular vesicular exosome
GO:0090003 IEA regulation of establishment of protein localization to plasma membrane
GO:1903208 IGI negative regulation of hydrogen peroxide-induced neuron death
GO:2000114 ISS regulation of establishment of cell polarity
GO:2000543 ISS positive regulation of gastrulation
GO:2001244 IEA positive regulation of intrinsic apoptotic signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000041619 gnb2l1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 protein_coding Danio_rerio
ENSG00000204628 GNB2L1 guanine nucleotide binding protein (G protein), beta polypeptide 2-like 1 protein_coding Homo_sapiens

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