C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: AKT1 substrate 1 (proline-rich)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000204673 AKT1S1 9606 - 19:49869033-49878459 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000344175 AKT1S1-001 49869039-49877340 protein_coding
  ENST00000391830 AKT1S1-006 49872970-49878459 protein_coding
  ENST00000391831 AKT1S1-004 49869046-49876249 protein_coding
  ENST00000391832 AKT1S1-003 49869039-49877279 protein_coding
  ENST00000391833 AKT1S1-005 49869038-49875285 protein_coding
  ENST00000391834 AKT1S1-201 49869033-49878356 protein_coding
  ENST00000391835 AKT1S1-002 49869046-49878028 protein_coding
  ENST00000482622 AKT1S1-007 49876658-49878356 processed_transcript
  ENST00000599525 AKT1S1-011 49873196-49873800 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000344175ENST00000391832ENST00000391835
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000344175 27.362±0.00 23.343±0.00 N/A 15.429±0.00 32.051±0.00 17.431±0.00 6.766±6.12 1.242±0.00 26.708±0.00 9.893±0.00 60.871±0.00 32.093±0.40 29.712±11.70 28.206±0.00
ENST00000391832 N/A N/A 0.766±0.00 N/A N/A 11.643±0.00 10.038±0.00 18.115±0.00 10.865±0.00 10.244±0.00 N/A 5.759±0.00 14.337±5.24 6.927±0.00
ENST00000391835 N/A N/A 0.381±0.00 0.778±0.00 N/A 0.705±0.00 N/A 1.396±0.00 0.504±0.00 N/A N/A 3.991±0.00 7.242±0.00 5.822±0.00

Conserved Regions

Gene is not located within a conserved region.

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IPI protein binding
GO:0005634 IEA nucleus
GO:0005737 IDA cytoplasm
GO:0005829 ISS cytosol
GO:0006469 IDA negative regulation of protein kinase activity
GO:0007173 TAS epidermal growth factor receptor signaling pathway
GO:0008543 TAS fibroblast growth factor receptor signaling pathway
GO:0031931 IDA TORC1 complex
GO:0032007 IEA:IDA negative regulation of TOR signaling
GO:0038095 TAS Fc-epsilon receptor signaling pathway
GO:0043234 IEA protein complex
GO:0043523 ISS regulation of neuron apoptotic process
GO:0045087 TAS innate immune response
GO:0045792 IDA negative regulation of cell size
GO:0048011 IEA:TAS neurotrophin TRK receptor signaling pathway
GO:0048015 TAS phosphatidylinositol-mediated signaling

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000074667 akt1s1 AKT1 substrate 1 (proline-rich) protein_coding Danio_rerio
ENSMUSG00000011096 Akt1s1 AKT1 substrate 1 (proline-rich) protein_coding Mus_musculus

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