C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: AKT1 substrate 1 (proline-rich)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000011096 Akt1s1 10090 + 7:44848991-44855421 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000054343 Akt1s1-201 44849224-44855421 protein_coding
  ENSMUST00000107880 Akt1s1-001 44850016-44855418 protein_coding
  ENSMUST00000107882 Akt1s1-003 44849629-44854736 protein_coding
  ENSMUST00000107885 Akt1s1-004 44848991-44855408 protein_coding
  ENSMUST00000127783 Akt1s1-009 44852571-44854686 protein_coding
  ENSMUST00000132884 Akt1s1-008 44851494-44852638 protein_coding
  ENSMUST00000136232 Akt1s1-007 44850396-44852863 protein_coding
  ENSMUST00000141311 Akt1s1-006 44850007-44854036 protein_coding
  ENSMUST00000142880 Akt1s1-010 44852920-44854644 retained_intron
  ENSMUST00000150335 Akt1s1-005 44849581-44852946 protein_coding
  ENSMUST00000152091 Akt1s1-002 44849344-44855417 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000054343ENSMUST00000107880ENSMUST00000107882ENSMUST00000107885ENSMUST00000127783ENSMUST00000150335ENSMUST00000152091
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000054343 27.112±6.30 55.302±4.87 38.449±2.61 34.803±6.43 29.461±7.42 30.900±4.85 14.588±3.76 26.222±6.41 24.348±4.12 24.024±3.22 62.770±5.73 34.105±7.48 40.475±13.81 4.113±0.00
ENSMUST00000107880 14.414±1.52 N/A N/A N/A N/A N/A 8.295±0.93 14.066±1.46 N/A N/A N/A N/A N/A 5.758±0.00
ENSMUST00000107882 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 29.813±0.00 N/A N/A
ENSMUST00000107885 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 7.658±2.84
ENSMUST00000127783 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 47.494±8.44 N/A
ENSMUST00000150335 N/A 135.303±20.44 N/A N/A 99.635±0.00 78.415±3.16 N/A N/A N/A N/A N/A 184.246±21.10 N/A N/A
ENSMUST00000152091 N/A N/A N/A N/A N/A N/A 4.314±0.00 N/A N/A N/A N/A N/A N/A 5.486±0.59

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006LB CIL_0006LB_0002 CGP 7:44840901-44855421

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005515 IEA protein binding
GO:0005634 IEA nucleus
GO:0005737 IEA cytoplasm
GO:0005829 IDA cytosol
GO:0006469 IEA negative regulation of protein kinase activity
GO:0007219 ISA Notch signaling pathway
GO:0031931 IEA TORC1 complex
GO:0032007 IEA negative regulation of TOR signaling
GO:0043234 IEA protein complex
GO:0043523 IDA regulation of neuron apoptotic process
GO:0045792 IEA negative regulation of cell size
GO:0048011 IEA neurotrophin TRK receptor signaling pathway

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000074667 akt1s1 AKT1 substrate 1 (proline-rich) protein_coding Danio_rerio
ENSG00000204673 AKT1S1 AKT1 substrate 1 (proline-rich) protein_coding Homo_sapiens

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