C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: protease, serine, 1 (trypsin 1)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000204983 PRSS1 9606 + 7:142749468-142763997 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000311737 PRSS1-001 142749479-142753070 protein_coding
  ENST00000463701 PRSS1-005 142751110-142753072 retained_intron
  ENST00000485223 PRSS1-002 142749472-142752008 retained_intron
  ENST00000486171 PRSS1-003 142749468-142753020 protein_coding
  ENST00000492062 PRSS1-004 142750665-142753069 protein_coding
  ENST00000497041 PRSS1-007 142749481-142751091 retained_intron
  ENST00000612126 PRSS1-201 142749479-142763997 protein_coding
  ENST00000619214 PRSS1-202 142749468-142753076 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdrenalBrainBreastKidneyOvaryTestisENST00000311737ENST00000463701ENST00000485223ENST00000486171ENST00000492062ENST00000497041ENST00000619214
Transcript ID Adrenal Brain Breast Kidney Ovary Testis
ENST00000311737 N/A N/A 6.538±0.00 N/A 2.071±0.00 N/A
ENST00000463701 0.059±0.00 N/A N/A N/A N/A N/A
ENST00000485223 N/A 0.039±0.00 N/A N/A N/A N/A
ENST00000486171 N/A N/A N/A N/A N/A 0.008±0.00
ENST00000492062 N/A N/A N/A N/A 0.216±0.00 N/A
ENST00000497041 N/A N/A N/A N/A N/A 0.027±0.00
ENST00000619214 N/A N/A N/A 0.176±0.00 N/A 0.014±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003A4 CIL_0003A4_0001 CGP 7:142748662-142774564
CIL_00039U CIL_00039U_0001 CGP 7:142749468-142871094

Gene Ontology

GO IDEvidence TypeGO Description
GO:0003824 IEA catalytic activity
GO:0004252 IEA:TAS serine-type endopeptidase activity
GO:0005576 NAS extracellular region
GO:0006508 IEA proteolysis
GO:0006766 TAS vitamin metabolic process
GO:0006767 TAS water-soluble vitamin metabolic process
GO:0007586 IEA digestion
GO:0009235 TAS cobalamin metabolic process
GO:0022617 TAS extracellular matrix disassembly
GO:0030198 TAS extracellular matrix organization
GO:0044281 TAS small molecule metabolic process
GO:0046872 IEA metal ion binding
GO:0070062 IDA extracellular vesicular exosome
GO:0072562 IDA blood microparticle

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000042993 try trypsin protein_coding Danio_rerio
ENSMUSG00000036938 Try5 trypsin 5 protein_coding Mus_musculus
ENSMUSG00000054106 Try4 trypsin 4 protein_coding Mus_musculus
ENSMUSG00000057163 Prss2 protease, serine 2 protein_coding Mus_musculus
ENSMUSG00000058119 Gm5771 predicted gene 5771 protein_coding Mus_musculus
ENSMUSG00000062751 Prss1 protease, serine 1 (trypsin 1) protein_coding Mus_musculus
ENSMUSG00000071517 Gm10334 predicted gene 10334 protein_coding Mus_musculus
ENSMUSG00000071519 Prss3 protease, serine 3 protein_coding Mus_musculus
ENSMUSG00000071521 Try10 trypsin 10 protein_coding Mus_musculus

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