C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: spire-type actin nucleation factor 2
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000204991 SPIRE2 9606 + 16:89818179-89871319 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000378247 SPIRE2-001 89828508-89871319 protein_coding
  ENST00000393062 SPIRE2-002 89828499-89870391 protein_coding
  ENST00000561883 SPIRE2-007 89854322-89856061 retained_intron
  ENST00000562029 SPIRE2-006 89861966-89870407 retained_intron
  ENST00000563972 SPIRE2-004 89828547-89847156 protein_coding
  ENST00000564878 SPIRE2-009 89818179-89850562 processed_transcript
  ENST00000565103 SPIRE2-010 89818250-89822530 processed_transcript
  ENST00000565628 SPIRE2-008 89863442-89870201 retained_intron
  ENST00000566337 SPIRE2-005 89828698-89859189 nonsense_mediated_decay
  ENST00000569108 SPIRE2-003 89849866-89870386 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000378247ENST00000393062ENST00000562029ENST00000563972ENST00000564878ENST00000566337ENST00000569108
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000378247 0.368±0.00 0.619±0.00 2.568±0.88 0.340±0.00 3.252±0.00 0.109±0.00 1.118±0.00 N/A N/A N/A 0.690±0.11 4.593±0.58 0.872±0.00
ENST00000393062 N/A N/A N/A N/A 1.308±0.00 N/A 0.213±0.00 0.318±0.00 N/A N/A 1.418±0.20 N/A 1.864±0.00
ENST00000562029 0.291±0.00 0.395±0.00 0.892±0.00 0.327±0.00 1.694±0.00 N/A 0.506±0.00 0.192±0.00 N/A N/A 0.333±0.27 N/A N/A
ENST00000563972 0.187±0.00 0.713±0.00 N/A 0.402±0.00 N/A 0.216±0.00 N/A 0.181±0.00 0.299±0.00 0.077±0.00 N/A N/A N/A
ENST00000564878 N/A N/A N/A N/A N/A N/A N/A 0.192±0.00 N/A N/A N/A N/A N/A
ENST00000566337 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.316±0.00 N/A N/A
ENST00000569108 0.699±0.00 0.306±0.00 N/A 0.635±0.15 N/A 0.233±0.00 0.738±0.39 N/A 3.051±0.00 N/A 0.591±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000069 CIL_000069_0001 CGP 16:89737549-89871319
CIL_00005J CIL_00005J_0001 CGP 16:89818179-89911384

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003779 IEA actin binding
GO:0005856 IEA cytoskeleton
GO:0005886 IEA plasma membrane
GO:0005938 ISS cell cortex
GO:0015031 IEA protein transport
GO:0016192 ISS vesicle-mediated transport
GO:0030036 IMP actin cytoskeleton organization
GO:0030659 ISS cytoplasmic vesicle membrane
GO:0032154 ISS cleavage furrow
GO:0036089 ISS cleavage furrow formation
GO:0040038 ISS polar body extrusion after meiotic divisions
GO:0046907 ISS intracellular transport
GO:0051295 IMP establishment of meiotic spindle localization
GO:0070649 ISS formin-nucleated actin cable assembly

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000003084 spire2 spire homolog 2 (Drosophila) protein_coding Danio_rerio
ENSMUSG00000010154 Spire2 spire homolog 2 (Drosophila) protein_coding Mus_musculus

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