C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: proteasome (prosome, macropain) subunit, beta type, 10
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000205220 PSMB10 9606 - 16:67934502-67937087 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000358514 PSMB10-001 67934502-67937087 protein_coding
  ENST00000570304 PSMB10-005 67935328-67936847 retained_intron
  ENST00000570985 PSMB10-003 67934506-67935795 retained_intron
  ENST00000574576 PSMB10-004 67934506-67935985 protein_coding
  ENST00000575556 PSMB10-002 67935549-67936864 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000358514ENST00000570304ENST00000570985ENST00000574576
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000358514 N/A N/A 0.750±0.00 1.263±0.00 2.727±0.00 0.638±0.00 N/A 1.516±0.00 3.585±0.00 N/A 23.231±22.66 N/A N/A
ENST00000570304 18.988±0.00 46.179±0.00 N/A 4.673±0.00 7.083±4.05 N/A 18.679±12.38 3.295±0.00 36.724±0.00 N/A 14.227±0.00 37.915±5.64 N/A
ENST00000570985 N/A N/A 13.253±8.69 41.759±0.00 17.961±0.00 16.818±14.84 21.446±13.68 14.252±9.92 67.505±0.00 10.282±0.10 37.066±13.91 56.809±20.19 15.850±0.00
ENST00000574576 20.445±0.00 65.437±0.00 N/A N/A 13.408±0.00 N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_000030 CIL_000030_0001 CGP 16:67934502-67944131

Gene Ontology
GO IDEvidence TypeGO Description
GO:0000082 TAS G1/S transition of mitotic cell cycle
GO:0000209 TAS protein polyubiquitination
GO:0000278 TAS mitotic cell cycle
GO:0000502 TAS proteasome complex
GO:0000902 IEA cell morphogenesis
GO:0002474 TAS antigen processing and presentation of peptide antigen via MHC class I
GO:0002479 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I, TAP-dependent
GO:0004298 IEA threonine-type endopeptidase activity
GO:0005654 TAS nucleoplasm
GO:0005829 TAS cytosol
GO:0005839 ISS:IEA proteasome core complex
GO:0006521 TAS regulation of cellular amino acid metabolic process
GO:0006915 TAS apoptotic process
GO:0006959 TAS humoral immune response
GO:0006977 TAS DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
GO:0010467 TAS gene expression
GO:0016032 TAS viral process
GO:0016070 TAS RNA metabolic process
GO:0016071 TAS mRNA metabolic process
GO:0031145 TAS anaphase-promoting complex-dependent proteasomal ubiquitin-dependent protein catabolic process
GO:0034641 TAS cellular nitrogen compound metabolic process
GO:0042098 IEA T cell proliferation
GO:0042590 TAS antigen processing and presentation of exogenous peptide antigen via MHC class I
GO:0042981 TAS regulation of apoptotic process
GO:0043066 TAS negative regulation of apoptotic process
GO:0044281 TAS small molecule metabolic process
GO:0051436 TAS negative regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051437 TAS positive regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051439 TAS regulation of ubiquitin-protein ligase activity involved in mitotic cell cycle
GO:0051603 IEA proteolysis involved in cellular protein catabolic process
GO:1990111 ISS spermatoproteasome complex

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000043781 PSMB10 proteasome (prosome, macropain) subunit, beta type, 10 protein_coding Danio_rerio
ENSMUSG00000031897 Psmb10 proteasome (prosome, macropain) subunit, beta type 10 protein_coding Mus_musculus

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