C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: ral guanine nucleotide dissociation stimulator-like 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000205517 RGL3 9606 - 19:11384341-11419342 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000380456 RGL3-001 11394057-11419342 protein_coding
  ENST00000393423 RGL3-002 11394325-11419328 protein_coding
  ENST00000453604 RGL3-004 11402228-11419314 retained_intron
  ENST00000561570 RGL3-009 11416850-11419317 processed_transcript
  ENST00000561687 RGL3-016 11406824-11416234 retained_intron
  ENST00000562663 RGL3-006 11384341-11419273 nonsense_mediated_decay
  ENST00000563436 RGL3-017 11416007-11416830 processed_transcript
  ENST00000563726 RGL3-007 11384512-11419310 nonsense_mediated_decay
  ENST00000565895 RGL3-012 11405212-11406943 retained_intron
  ENST00000566153 RGL3-008 11394056-11411270 retained_intron
  ENST00000566919 RGL3-013 11397244-11397769 retained_intron
  ENST00000567080 RGL3-015 11416039-11419314 protein_coding
  ENST00000567431 RGL3-011 11415937-11418573 protein_coding
  ENST00000568420 RGL3-010 11416463-11419305 retained_intron
  ENST00000568628 RGL3-014 11394064-11397546 processed_transcript
  ENST00000569439 RGL3-003 11406736-11419317 retained_intron
  ENST00000589032 RGL3-018 11402078-11406602 nonsense_mediated_decay

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENST00000380456ENST00000393423ENST00000561570ENST00000566153ENST00000567431ENST00000568628ENST00000569439
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000380456 2.744±0.00 0.838±0.00 1.491±0.00 0.568±0.00 0.750±0.00 N/A N/A N/A 1.321±0.00 N/A 2.223±1.21 4.114±1.54 N/A
ENST00000393423 N/A 1.319±0.00 N/A N/A N/A 1.702±0.00 N/A 8.844±0.00 N/A 2.021±0.00 N/A N/A 1.572±0.00
ENST00000561570 N/A N/A N/A N/A N/A 0.525±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000566153 N/A N/A N/A N/A 0.673±0.00 N/A 0.596±0.00 4.875±0.00 1.269±0.00 1.542±0.00 2.619±0.00 N/A 0.931±0.00
ENST00000567431 N/A N/A N/A 0.685±0.00 1.238±0.00 N/A N/A N/A N/A N/A N/A N/A N/A
ENST00000568628 N/A N/A N/A N/A N/A N/A 0.475±0.00 N/A N/A N/A N/A N/A N/A
ENST00000569439 N/A N/A 2.639±0.00 N/A N/A N/A N/A 0.623±0.00 1.345±0.00 N/A 1.901±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_00016B CIL_00016B_0001 CGP 19:11374685-11384342
CIL_0003RI CIL_0003RI_0001 CGP 19:11377205-11419342
CIL_0004G4 CIL_0004G4_0001 CGP 19:11384341-11435782

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005085 IEA guanyl-nucleotide exchange factor activity
GO:0005515 IEA protein binding
GO:0005622 IEA intracellular
GO:0007165 IEA signal transduction
GO:0007264 IEA small GTPase mediated signal transduction
GO:0008321 IEA Ral guanyl-nucleotide exchange factor activity
GO:0017016 IEA Ras GTPase binding
GO:0032852 IEA positive regulation of Ral GTPase activity
GO:0043547 IEA positive regulation of GTPase activity
GO:0051056 IEA regulation of small GTPase mediated signal transduction

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000022185 RGL3 (1 of 2) ral guanine nucleotide dissociation stimulator-like 3 protein_coding Danio_rerio
ENSDARG00000071213 rgl3a ral guanine nucleotide dissociation stimulator-like 3a protein_coding Danio_rerio
ENSMUSG00000040146 Rgl3 ral guanine nucleotide dissociation stimulator-like 3 protein_coding Mus_musculus

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