C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: DENN/MADD domain containing 6B
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000205593 DENND6B 9606 - 22:50309030-50327060 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000413817 DENND6B-001 50309030-50327060 protein_coding
  ENST00000433760 DENND6B-004 50314822-50319095 protein_coding
  ENST00000460087 DENND6B-003 50316654-50318970 retained_intron
  ENST00000471942 DENND6B-005 50314203-50318967 retained_intron
  ENST00000495607 DENND6B-002 50311966-50326977 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000413817ENST00000433760ENST00000460087ENST00000471942ENST00000495607
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000413817 N/A N/A 0.599±0.00 1.813±0.57 0.293±0.26 0.023±0.00 0.091±0.07 0.403±0.00 0.030±0.00 N/A N/A 1.427±0.00 0.027±0.00 N/A
ENST00000433760 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.323±0.00 3.806±0.00
ENST00000460087 N/A N/A N/A N/A N/A N/A 0.358±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000471942 N/A N/A N/A N/A 0.235±0.00 N/A N/A N/A N/A N/A N/A 1.422±0.00 0.480±0.29 N/A
ENST00000495607 0.516±0.00 2.787±0.00 N/A 2.665±2.16 0.790±0.75 1.055±0.00 0.268±0.00 1.335±0.00 0.242±0.03 8.960±0.00 0.424±0.00 2.257±1.62 0.409±0.19 6.416±1.07

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0000V2 CIL_0000V2_0002 CGP 22:50309030-50445090

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005768 IEA endosome
GO:0017112 IDA Rab guanyl-nucleotide exchange factor activity
GO:0032851 IDA positive regulation of Rab GTPase activity

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000011605 dennd6b DENN/MADD domain containing 6B protein_coding Danio_rerio
ENSMUSG00000015377 Dennd6b DENN/MADD domain containing 6B protein_coding Mus_musculus

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