C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: leucine carboxyl methyltransferase 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000205629 LCMT1 9606 + 16:25111729-25178231 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000380962 LCMT1-003 25111731-25178231 nonsense_mediated_decay
  ENST00000380966 LCMT1-011 25111735-25178023 protein_coding
  ENST00000399069 LCMT1-001 25111729-25178231 protein_coding
  ENST00000564011 LCMT1-002 25111735-25178198 nonsense_mediated_decay
  ENST00000570981 LCMT1-004 25111932-25140503 protein_coding
  ENST00000572761 LCMT1-007 25164598-25169545 protein_coding
  ENST00000572869 LCMT1-012 25151531-25178045 processed_transcript
  ENST00000573435 LCMT1-013 25151525-25161206 processed_transcript
  ENST00000574450 LCMT1-008 25174746-25178228 retained_intron
  ENST00000575396 LCMT1-009 25164690-25178226 protein_coding
  ENST00000576382 LCMT1-005 25140055-25161168 retained_intron
  ENST00000576625 LCMT1-010 25140176-25178082 nonsense_mediated_decay
  ENST00000577157 LCMT1-006 25111745-25158931 processed_transcript

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENST00000380962ENST00000380966ENST00000399069ENST00000570981ENST00000572869ENST00000573435ENST00000575396ENST00000576625ENST00000577157
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENST00000380962 N/A 2.586±0.00 N/A N/A 2.056±0.00 N/A N/A N/A 0.537±0.00 N/A N/A N/A 6.480±2.42 N/A
ENST00000380966 N/A N/A N/A N/A 1.716±0.00 N/A 0.753±0.00 N/A N/A N/A N/A N/A N/A N/A
ENST00000399069 8.071±0.00 2.147±0.00 N/A 15.491±9.01 6.685±0.00 5.437±4.29 3.594±3.33 6.534±6.46 1.390±0.88 5.065±0.00 16.643±0.00 11.640±9.56 17.336±4.78 21.045±4.57
ENST00000570981 N/A N/A 0.503±0.00 N/A N/A N/A N/A N/A N/A N/A N/A 1.671±0.00 N/A N/A
ENST00000572869 4.352±0.00 5.578±0.00 0.669±0.00 N/A N/A 7.763±0.00 N/A N/A N/A N/A N/A N/A N/A 13.626±0.00
ENST00000573435 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 31.600±0.00 101.502±0.00 103.835±0.00
ENST00000575396 N/A N/A N/A N/A N/A N/A N/A 16.278±0.00 4.876±0.00 6.638±0.00 N/A N/A N/A N/A
ENST00000576625 N/A N/A 0.779±0.00 3.972±0.00 4.532±0.00 4.089±0.00 1.075±0.00 0.617±0.00 3.081±0.00 N/A 6.042±1.78 6.333±1.48 15.535±0.00 24.760±0.00
ENST00000577157 N/A N/A N/A N/A N/A 4.656±0.00 N/A N/A N/A N/A N/A N/A N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003XC CIL_0003XC_0001 CGP 16:24919385-25178231
CIL_0003XX CIL_0003XX_0001 CGP 16:25111729-25228940

Gene Ontology
GO IDEvidence TypeGO Description
GO:0003880 IDA protein C-terminal carboxyl O-methyltransferase activity
GO:0005515 IPI protein binding
GO:0005829 IEA cytosol
GO:0006464 TAS cellular protein modification process
GO:0006479 IMP protein methylation
GO:0006481 IDA C-terminal protein methylation
GO:0008168 IEA methyltransferase activity
GO:0008276 IEA protein methyltransferase activity
GO:0008757 TAS S-adenosylmethionine-dependent methyltransferase activity
GO:0010906 IEA regulation of glucose metabolic process
GO:0031333 IMP negative regulation of protein complex assembly
GO:0032259 IEA methylation
GO:0042981 IMP regulation of apoptotic process
GO:0090266 IMP regulation of mitotic cell cycle spindle assembly checkpoint

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000045140 lcmt1 leucine carboxyl methyltransferase 1 protein_coding Danio_rerio
ENSMUSG00000030763 Lcmt1 leucine carboxyl methyltransferase 1 protein_coding Mus_musculus

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