C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: acid-sensing (proton-gated) ion channel 3
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000213199 ASIC3 9606 + 7:151048292-151052756 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000297512 ASIC3-005 151048886-151052754 protein_coding
  ENST00000349064 ASIC3-003 151048688-151052753 protein_coding
  ENST00000357922 ASIC3-001 151048292-151052753 protein_coding
  ENST00000377904 ASIC3-002 151048518-151052754 nonsense_mediated_decay
  ENST00000468325 ASIC3-004 151048767-151052753 nonsense_mediated_decay
  ENST00000474135 ASIC3-006 151050078-151050864 retained_intron
  ENST00000485929 ASIC3-009 151050920-151052754 protein_coding
  ENST00000490540 ASIC3-007 151051213-151052756 protein_coding
  ENST00000498105 ASIC3-008 151051234-151052732 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverMuscleOvaryPlacentaTestisENST00000297512ENST00000349064ENST00000357922ENST00000377904ENST00000468325ENST00000474135ENST00000485929ENST00000490540ENST00000498105
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Muscle Ovary Placenta Testis
ENST00000297512 N/A N/A N/A N/A N/A 0.561±0.00 N/A 0.802±0.00 0.069±0.00 0.122±0.00 0.361±0.00 N/A N/A
ENST00000349064 0.040±0.00 N/A N/A N/A N/A N/A 0.279±0.05 0.462±0.00 N/A N/A 0.990±0.37 0.201±0.03 1.777±0.00
ENST00000357922 N/A N/A N/A N/A 0.191±0.00 N/A N/A N/A 0.048±0.00 N/A 0.291±0.00 0.104±0.00 1.798±0.00
ENST00000377904 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 0.280±0.00 N/A N/A
ENST00000468325 N/A N/A 0.097±0.00 N/A 0.041±0.00 N/A N/A 0.429±0.00 0.175±0.00 0.281±0.11 0.556±0.00 0.184±0.00 N/A
ENST00000474135 N/A 0.491±0.00 N/A N/A N/A 0.246±0.00 N/A N/A N/A N/A 0.991±0.00 N/A N/A
ENST00000485929 N/A N/A N/A N/A N/A N/A N/A N/A N/A N/A 1.031±0.00 0.116±0.00 N/A
ENST00000490540 N/A N/A N/A 2.325±0.00 N/A 0.578±0.00 N/A N/A 0.142±0.00 0.448±0.00 N/A N/A N/A
ENST00000498105 N/A 0.249±0.00 N/A 1.730±0.00 N/A N/A N/A 0.374±0.09 N/A N/A 0.863±0.00 0.175±0.00 2.447±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008T1 CIL_0008T1_0001 VISTA 7:150668461-151272977
CIL_0004O7 CIL_0004O7_0001 CGP 7:151028422-151052756
CIL_0004ET CIL_0004ET_0001 CGP 7:151048292-151058530

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005261 TAS cation channel activity
GO:0005272 TAS:IEA sodium channel activity
GO:0005515 IEA protein binding
GO:0005737 IEA cytoplasm
GO:0005886 TAS plasma membrane
GO:0005887 IEA integral component of plasma membrane
GO:0006810 TAS transport
GO:0006812 IEA cation transport
GO:0006814 IEA sodium ion transport
GO:0007165 TAS signal transduction
GO:0007600 TAS sensory perception
GO:0009408 IEA response to heat
GO:0009612 IEA response to mechanical stimulus
GO:0010447 IEA response to acidic pH
GO:0015280 IEA ligand-gated sodium channel activity
GO:0016020 IEA membrane
GO:0016021 IEA integral component of membrane
GO:0030165 IEA PDZ domain binding
GO:0034220 TAS ion transmembrane transport
GO:0035725 IEA sodium ion transmembrane transport
GO:0042930 IEA enterobactin transport
GO:0042931 IEA enterobactin transporter activity
GO:0050907 IEA detection of chemical stimulus involved in sensory perception
GO:0050915 IMP sensory perception of sour taste
GO:0050961 IEA detection of temperature stimulus involved in sensory perception
GO:0050965 IEA detection of temperature stimulus involved in sensory perception of pain
GO:0050966 IEA detection of mechanical stimulus involved in sensory perception of pain
GO:0050968 IEA detection of chemical stimulus involved in sensory perception of pain
GO:0050974 IEA detection of mechanical stimulus involved in sensory perception
GO:0055085 TAS transmembrane transport
GO:0098655 TAS cation transmembrane transport

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSMUSG00000038276 Asic3 acid-sensing (proton-gated) ion channel 3 protein_coding Mus_musculus

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