Institute of Cardiovascular Regeneration Webtool Repository

C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info
Description:	leukotriene C4 synthase
Gene Accession	Gene Name	Tax ID	Strand	Position	Gene Biotype
ENSG00000213316	LTC4S	9606	+	5:179793980-179796647	protein_coding
	Transcript Accession		Transcript Name	Position	Transcript Biotype
	ENST00000292596		LTC4S-001	179793986-179796512	protein_coding
	ENST00000401985		LTC4S-003	179793993-179796510	protein_coding
	ENST00000465572		LTC4S-002	179793980-179796647	retained_intron
	ENST00000466071		LTC4S-005	179794013-179796021	retained_intron
	ENST00000486713		LTC4S-004	179794033-179796159	retained_intron
	ENST00000505170		LTC4S-008	179793985-179796444	nonsense_mediated_decay
	ENST00000509898		LTC4S-006	179795555-179796375	retained_intron
	ENST00000510544		LTC4S-007	179795308-179796314	retained_intron

Expression Patterns

No expression data.

Conserved Regions
Gene is not located within a conserved region.

Gene Ontology
GO ID	Evidence Type	GO Description
GO:0004364	IBA	glutathione transferase activity
GO:0004464	IDA	leukotriene-C4 synthase activity
GO:0004602	IBA	glutathione peroxidase activity
GO:0005515	IPI	protein binding
GO:0005635	IDA	nuclear envelope
GO:0005783	IDA	endoplasmic reticulum
GO:0006691	IDA	leukotriene metabolic process
GO:0008047	IEA	enzyme activator activity
GO:0008289	IDA	lipid binding
GO:0016021	IEA	integral component of membrane
GO:0019369	TAS	arachidonic acid metabolic process
GO:0019370	IBA	leukotriene biosynthetic process
GO:0019372	TAS	lipoxygenase pathway
GO:0043085	IEA	positive regulation of catalytic activity
GO:0043231	TAS	intracellular membrane-bounded organelle
GO:0044281	TAS	small molecule metabolic process
GO:0055114	IBA	oxidation-reduction process
GO:2001300	TAS	lipoxin metabolic process

Homologs
ENSEMBL Accession	Gene Name	Description	Biotype	Species
ENSDARG00000062598	ltc4s	leukotriene C4 synthase	protein_coding	Danio_rerio
ENSMUSG00000020377	Ltc4s	leukotriene C4 synthase	protein_coding	Mus_musculus

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