C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: leukotriene C4 synthase
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSMUSG00000020377 Ltc4s 10090 - 11:50236469-50238616 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENSMUST00000101265 Ltc4s-003 50236469-50238471 protein_coding
  ENSMUST00000102772 Ltc4s-001 50236472-50238532 protein_coding
  ENSMUST00000125555 Ltc4s-002 50236472-50238616 protein_coding

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBladderBrainBreastColonHeartKidneyLiverLungMuscleOvaryPlacentaTestisENSMUST00000101265ENSMUST00000102772ENSMUST00000125555
Transcript ID Adipose Adrenal Bladder Brain Breast Colon Heart Kidney Liver Lung Muscle Ovary Placenta Testis
ENSMUST00000101265 N/A N/A N/A N/A N/A 4.535±0.00 N/A N/A 0.320±0.00 N/A 0.475±0.00 2.586±0.00 N/A N/A
ENSMUST00000102772 149.023±85.13 38.229±15.85 16.419±7.23 1.814±0.69 97.227±21.70 10.517±3.19 5.018±0.62 14.977±2.22 0.733±0.20 40.268±2.75 0.923±0.51 10.665±4.95 9.412±5.71 3.979±1.97
ENSMUST00000125555 N/A N/A N/A 1.026±0.00 10.150±0.00 1.838±0.47 N/A 1.940±0.00 0.145±0.02 N/A 0.281±0.13 1.254±0.56 1.088±0.00 N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0003QL CIL_0003QL_0002 CGP 11:50236469-50292311

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004364 IBA glutathione transferase activity
GO:0004464 IDA leukotriene-C4 synthase activity
GO:0004602 IBA glutathione peroxidase activity
GO:0005515 IEA protein binding
GO:0005635 IBA nuclear envelope
GO:0005783 IBA endoplasmic reticulum
GO:0006691 IDA leukotriene metabolic process
GO:0008047 IEA enzyme activator activity
GO:0008289 IDA lipid binding
GO:0016021 IEA integral component of membrane
GO:0019370 IBA leukotriene biosynthetic process
GO:0043085 IEA positive regulation of catalytic activity
GO:0055114 IBA oxidation-reduction process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000062598 ltc4s leukotriene C4 synthase protein_coding Danio_rerio
ENSG00000213316 LTC4S leukotriene C4 synthase protein_coding Homo_sapiens

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