C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: glutathione S-transferase mu 2 (muscle)
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000213366 GSTM2 9606 + 1:109668022-109709551 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000241337 GSTM2-002 109668066-109675286 protein_coding
  ENST00000369827 GSTM2-201 109668036-109675283 protein_coding
  ENST00000369829 GSTM2-004 109668092-109673525 protein_coding
  ENST00000369831 GSTM2-001 109668022-109709549 protein_coding
  ENST00000414179 GSTM2-003 109668088-109683584 protein_coding
  ENST00000442650 GSTM2-202 109668022-109683997 protein_coding
  ENST00000460717 GSTM2-005 109668051-109702442 protein_coding
  ENST00000464206 GSTM2-006 109668054-109670023 processed_transcript
  ENST00000467579 GSTM2-009 109668083-109671486 protein_coding
  ENST00000472225 GSTM2-008 109669547-109674864 retained_intron
  ENST00000476040 GSTM2-007 109668061-109670099 retained_intron
  ENST00000481656 GSTM2-010 109668057-109668848 retained_intron
  ENST00000496578 GSTM2-011 109670659-109675079 retained_intron
  ENST00000568786 GSTM2-012 109668113-109669476 retained_intron
  ENST00000624726 GSTM2-013 109705231-109709551 TEC

Expression Patterns

Heat Map
Numeric Values
Transcript'; BladderBrainBreastColonHeartLiverLungMuscleOvaryPlacentaTestisENST00000241337ENST00000467579ENST00000472225ENST00000476040ENST00000496578ENST00000624726
Transcript ID Bladder Brain Breast Colon Heart Liver Lung Muscle Ovary Placenta Testis
ENST00000241337 N/A N/A 28.198±0.00 6.278±0.00 16.016±0.00 N/A 14.561±0.00 10.856±0.00 35.866±10.27 4.081±0.14 10.052±0.00
ENST00000467579 6.863±0.00 13.183±0.00 9.530±0.00 N/A 7.289±0.00 11.270±0.00 13.678±0.00 30.763±0.00 6.313±0.00 N/A N/A
ENST00000472225 N/A N/A N/A N/A N/A N/A 14.172±0.00 N/A 28.299±0.00 N/A N/A
ENST00000476040 5.510±0.00 N/A N/A 7.049±0.00 N/A 6.825±0.00 N/A N/A 18.503±14.62 N/A N/A
ENST00000496578 N/A N/A N/A N/A N/A N/A N/A N/A 38.891±0.00 N/A N/A
ENST00000624726 N/A N/A N/A N/A N/A N/A N/A N/A 5.040±0.00 N/A N/A

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0006TX CIL_0006TX_0002 CGP 1:109616104-109674836
CIL_0006TW CIL_0006TW_0005 CGP 1:109656081-109709551
CIL_0006TW CIL_0006TW_0006 CGP 1:109668022-109709551

Gene Ontology
GO IDEvidence TypeGO Description
GO:0004364 IDA glutathione transferase activity
GO:0005102 IPI receptor binding
GO:0005515 IEA protein binding
GO:0005737 IDA cytoplasm
GO:0005829 TAS cytosol
GO:0006749 IDA glutathione metabolic process
GO:0006805 TAS xenobiotic metabolic process
GO:0008152 IEA metabolic process
GO:0010880 IDA regulation of release of sequestered calcium ion into cytosol by sarcoplasmic reticulum
GO:0010881 IC regulation of cardiac muscle contraction by regulation of the release of sequestered calcium ion
GO:0014809 IC regulation of skeletal muscle contraction by regulation of release of sequestered calcium ion
GO:0016529 IDA sarcoplasmic reticulum
GO:0018916 IDA nitrobenzene metabolic process
GO:0019899 IPI enzyme binding
GO:0042178 IDA xenobiotic catabolic process
GO:0042803 IPI protein homodimerization activity
GO:0043295 IDA glutathione binding
GO:0044281 TAS small molecule metabolic process
GO:0055119 TAS relaxation of cardiac muscle
GO:0060315 IDA negative regulation of ryanodine-sensitive calcium-release channel activity
GO:0060316 IDA positive regulation of ryanodine-sensitive calcium-release channel activity
GO:0070062 IDA extracellular vesicular exosome
GO:0070458 IDA cellular detoxification of nitrogen compound
GO:0071313 IDA cellular response to caffeine
GO:1901687 TAS glutathione derivative biosynthetic process

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000029473 zgc:173994 zgc:173994 protein_coding Danio_rerio
ENSDARG00000042533 gstm glutathione S-transferase M protein_coding Danio_rerio
ENSDARG00000088116 gstm3 glutathione S-transferase M3 (brain) protein_coding Danio_rerio
ENSMUSG00000004035 Gstm7 glutathione S-transferase, mu 7 protein_coding Mus_musculus

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