C-It-Loci: A knowledge database for tissue-enriched loci.

Institute of Cardiovascular Regeneration, Goethe-University Frankfurt am Main

Gene Info

Description: signal-induced proliferation-associated 1
Gene AccessionGene NameTax IDStrandPositionGene Biotype
ENSG00000213445 SIPA1 9606 + 11:65585395-65650930 protein_coding
  Transcript Accession Transcript Name Position Transcript Biotype
  ENST00000394224 SIPA1-003 65640121-65650918 protein_coding
  ENST00000394227 SIPA1-201 65585395-65650920 protein_coding
  ENST00000526137 SIPA1-005 65638152-65640940 protein_coding
  ENST00000527525 SIPA1-002 65639866-65650880 protein_coding
  ENST00000528699 SIPA1-010 65650282-65650918 retained_intron
  ENST00000529725 SIPA1-009 65649686-65650587 retained_intron
  ENST00000530226 SIPA1-007 65645811-65646710 retained_intron
  ENST00000531339 SIPA1-008 65647366-65650479 retained_intron
  ENST00000533361 SIPA1-004 65638136-65641229 protein_coding
  ENST00000534313 SIPA1-001 65638097-65650930 protein_coding
  ENST00000534406 SIPA1-006 65642118-65642553 retained_intron

Expression Patterns

Heat Map
Numeric Values
Transcript'; AdiposeAdrenalBrainBreastColonHeartKidneyLiverLungOvaryPlacentaTestisENST00000394227ENST00000534313
Transcript ID Adipose Adrenal Brain Breast Colon Heart Kidney Liver Lung Ovary Placenta Testis
ENST00000394227 N/A N/A N/A N/A 0.965±0.00 N/A N/A N/A N/A 10.855±0.00 14.238±1.46 N/A
ENST00000534313 17.484±0.00 43.656±0.00 4.190±0.00 10.374±0.00 N/A 0.756±0.00 11.901±0.00 5.128±0.00 33.990±0.00 7.303±6.39 11.997±0.43 9.044±0.00

Conserved Regions

Region IDSub-RegionRegion TypePosition
CIL_0008W1 CIL_0008W1_0001 VISTA 11:65187233-65790923
CIL_0004VX CIL_0004VX_0002 CGP 11:65572349-65592650

Gene Ontology
GO IDEvidence TypeGO Description
GO:0005096 TAS:IEA GTPase activator activity
GO:0005515 IPI:IEA protein binding
GO:0005634 IC nucleus
GO:0005829 TAS cytosol
GO:0007010 NAS cytoskeleton organization
GO:0007162 NAS negative regulation of cell adhesion
GO:0007165 TAS signal transduction
GO:0008022 IEA protein C-terminus binding
GO:0008283 TAS cell proliferation
GO:0016020 IEA membrane
GO:0030133 IEA transport vesicle
GO:0030308 NAS negative regulation of cell growth
GO:0032854 NAS positive regulation of Rap GTPase activity
GO:0035556 NAS intracellular signal transduction
GO:0042631 IEA cellular response to water deprivation
GO:0043234 IEA protein complex
GO:0043547 TAS positive regulation of GTPase activity
GO:0045786 NAS negative regulation of cell cycle
GO:0046582 NAS Rap GTPase activator activity
GO:0051056 IEA regulation of small GTPase mediated signal transduction
GO:0051726 IEA regulation of cell cycle

Homologs

ENSEMBL Accession Gene Name Description Biotype Species
ENSDARG00000076697 SIPA1 signal-induced proliferation-associated 1 protein_coding Danio_rerio
ENSMUSG00000056917 Sipa1 signal-induced proliferation associated gene 1 protein_coding Mus_musculus

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